Difference between revisions of "Reproductive Hormones Overview - Anatomy & Physiology"
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Line 36: | Line 36: | ||
| OT | | OT | ||
| E2 | | E2 | ||
− | | | + | | P4 |
− | | | + | | T |
+ | | | ||
+ | | | ||
+ | | PGF2α | ||
+ | | PGE2 | ||
+ | | hCG | ||
+ | | eCG | ||
+ | | PL | ||
|- | |- | ||
− | | ''' | + | | '''Biochemical Classification''' |
− | | | + | | Neuropeptide (decapeptide) |
− | | | + | | Glycoprotein |
− | | | + | | Glycoprotein |
− | | | + | | Protein |
− | | | + | | Neuropeptide (Octapeptide) |
− | | | + | | Steroid |
− | | | + | | Steroid |
− | | | + | | Steroid |
+ | | Glycoprotein | ||
+ | | Glycoprotein | ||
+ | | Prostaglandin (C20 fatty acid) | ||
+ | | Prostaglandin (C20 fatty acid) | ||
+ | | Glycoprotein | ||
+ | | Glycoprotein | ||
+ | | Protein | ||
|- | |- | ||
− | | ''' | + | | '''Source''' |
− | | | + | | Hypothalamic Surge and Tonic Centres |
− | | | + | | Anterior Pituitary (Gonadotroph Cells) |
− | | | + | | Anterior Pituitary (Gonadotroph Cells) |
− | | | + | | Anterior Pituitary (Lactotroph Cells) |
− | | | + | | Synthesized in the Hypothalamus, Stored in the Posterior Pituitary, Synthesized by the Corpus Luteum |
− | | | + | | Granulosa Cells of Follicle, Placenta and Sertoli Cells of Testes |
− | | | + | | Corpus Luteum and Placenta |
− | | | + | | Interstitial Leydig Cells of Testes, Theca Interna Cells of the Follicle |
+ | | Granulosa Cells (female), Sertoli Cells (male) | ||
+ | | Granulosa Cells (female), Sertoli Cells (male) | ||
+ | | Uterine Endometrium, Vesicular Glands | ||
+ | | Ovary, Uterus, Embryonic Membranes | ||
+ | | Trophoblast Cells of the Blastocyst (Chorion) | ||
+ | | Chorionic Girdle Cells | ||
+ | | Placenta | ||
|- | |- | ||
− | | ''' | + | | '''Male Target Tissue''' |
− | | | + | | Anterior Pituitary (Gonadotroph Cells) |
− | | | + | | Testes (Leydig Cells) |
− | | | + | | Testes (Sertoli Cells) |
− | | | + | | Testes, Brain |
− | | | + | | Smooth Muscle of Epididymal Tail, Ductus Deferens, Ampulla |
− | | | + | | Brain, Inhibits Long Bone Growth |
− | | | + | | Accessory Sex Glands, Tunica Dartos (Scrotum), Semniferous Epithelium, Skeletal Muscle |
− | | | + | | Anterior Pituitary (Gonadotroph Cells) |
+ | | Anterior Pituitary (Gonadotroph Cells) | ||
+ | | Epididymis | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
|- | |- | ||
− | | ''' | + | | '''Female Target Tissue''' |
− | | | + | | Anterior Pituitary (Gonadotroph Cells) |
− | | | + | | Ovary (Theca Interna and Luteal Cells) |
− | | | + | | Ovary (Granulosa Cells) |
− | | | + | | Mammary Cells, Corpus Luteum in Rodents |
− | | | + | | Uterine Myometrium and Endometrium, Myoepithelial Cells of Mammary Glands |
− | | | + | | Hypothalamus, Entire Tract, Mammary Gland |
− | | | + | | Uterine Endometrium, Mammary Gland, Myometrium, Hypothalamus |
− | | | + | | Brain, Skeletal Muscle, Granulosa Cells |
+ | | Anterior Pituitary (Gonadotroph Cells) | ||
+ | | Anterior Pituitary (Gonadotroph Cells) | ||
+ | | Corpus Luteum, Uterine Myometrium, Ovulatory Follicles | ||
+ | | Corpus Luteum, Oviduct | ||
+ | | Ovary | ||
+ | | Ovary | ||
+ | | Mammary Gland | ||
|- | |- | ||
− | | ''' | + | | '''Male Primary Action''' |
− | | | + | | Release of FSH and LH from the Anterior Pituitary Gland |
− | | | + | | Stimulates Testosterone Production |
− | | | + | | Sertoli Cell Function |
− | | | + | | Induce Maternal Behaviour |
− | | | + | | PGF2α Synthesis, Pre-Ejaculatory Movement of Spermatozoa |
− | | | + | | Sexual Behaviour |
− | | | + | | |
− | | | + | | Anabolic Growth, Promotes Spermatogenesis, Promotes Secretion of Accessory Sex Glands |
+ | | Inhibits FSH Secretion | ||
+ | | Stimulates FSH Secretion | ||
+ | | Affects Metabolic Activity of Spermatozoa, Epididymal Contractions | ||
+ | | | ||
+ | | Increased Growth of Foetal Testes | ||
+ | | | ||
+ | | | ||
|- | |- | ||
− | | ''' | + | | '''Female Primary Action''' |
− | | | + | | Release of FSH and LH from Anterior Pituitary Gland |
− | | | + | | Stimulates Ovulation, Formation of Corpora Lutea and Progesterone Secretion |
− | | | + | | Follicular Development, Oestradiol Synthesis |
− | | | + | | Lactation, Maternal Behaviour, Corpora Lutea Function (some species) |
− | | | + | | Uterine Motility, Uterine PGF2α Synthesis, Milk Ejection |
− | | | + | | Sexual Behaviour, GnRH, Elevated Secretory Activity of Tract, Enhanced Uterine Motility |
− | + | | Endometrial Secretion, Inhibits GnRH Release,Inhibits Reproductive Behaviour, Maintenance of Pregnancy | |
− | + | | Substrate For E2 Synthesis, Abnormal Masculinization | |
− | + | | Inhibits FSH Secretion | |
− | | | + | | Stimulates FSH Secretion |
− | | | + | | Luteolysis, Uterine Tone and Contraction, Ovulation |
− | | | + | |Ovulation, Corpus Luteum Secretion of Progesterone |
− | | | + | | Facilitates Ovarian Production of Progesterone |
− | | | + | | Formation of Accessory Corpora Lutea |
− | | | + | | Mammary Stimulation |
− | | | ||
− | | | ||
− | | | ||
| | | | ||
|} | |} |
Revision as of 09:21, 5 September 2008
|
Name of Hormone | Gonadotrophin Releasing Hormone | Leutinizing Hormone | Follicle Stimulating Hormone | Prolactin | Oxytocin | Oestradiol | Progesterone | Testosterone | Inhibin | Activin | Prostaglandin F2α | Human Chorionic Gonadotrophin | Equine Chorionic Gonadotrophin | Placental Lactogen | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbreviation | GnRH | LH | FSH | PRL | OT | E2 | P4 | T | PGF2α | PGE2 | hCG | eCG | PL | |||
Biochemical Classification | Neuropeptide (decapeptide) | Glycoprotein | Glycoprotein | Protein | Neuropeptide (Octapeptide) | Steroid | Steroid | Steroid | Glycoprotein | Glycoprotein | Prostaglandin (C20 fatty acid) | Prostaglandin (C20 fatty acid) | Glycoprotein | Glycoprotein | Protein | |
Source | Hypothalamic Surge and Tonic Centres | Anterior Pituitary (Gonadotroph Cells) | Anterior Pituitary (Gonadotroph Cells) | Anterior Pituitary (Lactotroph Cells) | Synthesized in the Hypothalamus, Stored in the Posterior Pituitary, Synthesized by the Corpus Luteum | Granulosa Cells of Follicle, Placenta and Sertoli Cells of Testes | Corpus Luteum and Placenta | Interstitial Leydig Cells of Testes, Theca Interna Cells of the Follicle | Granulosa Cells (female), Sertoli Cells (male) | Granulosa Cells (female), Sertoli Cells (male) | Uterine Endometrium, Vesicular Glands | Ovary, Uterus, Embryonic Membranes | Trophoblast Cells of the Blastocyst (Chorion) | Chorionic Girdle Cells | Placenta | |
Male Target Tissue | Anterior Pituitary (Gonadotroph Cells) | Testes (Leydig Cells) | Testes (Sertoli Cells) | Testes, Brain | Smooth Muscle of Epididymal Tail, Ductus Deferens, Ampulla | Brain, Inhibits Long Bone Growth | Accessory Sex Glands, Tunica Dartos (Scrotum), Semniferous Epithelium, Skeletal Muscle | Anterior Pituitary (Gonadotroph Cells) | Anterior Pituitary (Gonadotroph Cells) | Epididymis | ||||||
Female Target Tissue | Anterior Pituitary (Gonadotroph Cells) | Ovary (Theca Interna and Luteal Cells) | Ovary (Granulosa Cells) | Mammary Cells, Corpus Luteum in Rodents | Uterine Myometrium and Endometrium, Myoepithelial Cells of Mammary Glands | Hypothalamus, Entire Tract, Mammary Gland | Uterine Endometrium, Mammary Gland, Myometrium, Hypothalamus | Brain, Skeletal Muscle, Granulosa Cells | Anterior Pituitary (Gonadotroph Cells) | Anterior Pituitary (Gonadotroph Cells) | Corpus Luteum, Uterine Myometrium, Ovulatory Follicles | Corpus Luteum, Oviduct | Ovary | Ovary | Mammary Gland | |
Male Primary Action | Release of FSH and LH from the Anterior Pituitary Gland | Stimulates Testosterone Production | Sertoli Cell Function | Induce Maternal Behaviour | PGF2α Synthesis, Pre-Ejaculatory Movement of Spermatozoa | Sexual Behaviour | Anabolic Growth, Promotes Spermatogenesis, Promotes Secretion of Accessory Sex Glands | Inhibits FSH Secretion | Stimulates FSH Secretion | Affects Metabolic Activity of Spermatozoa, Epididymal Contractions | Increased Growth of Foetal Testes | |||||
Female Primary Action | Release of FSH and LH from Anterior Pituitary Gland | Stimulates Ovulation, Formation of Corpora Lutea and Progesterone Secretion | Follicular Development, Oestradiol Synthesis | Lactation, Maternal Behaviour, Corpora Lutea Function (some species) | Uterine Motility, Uterine PGF2α Synthesis, Milk Ejection | Sexual Behaviour, GnRH, Elevated Secretory Activity of Tract, Enhanced Uterine Motility | Endometrial Secretion, Inhibits GnRH Release,Inhibits Reproductive Behaviour, Maintenance of Pregnancy | Substrate For E2 Synthesis, Abnormal Masculinization | Inhibits FSH Secretion | Stimulates FSH Secretion | Luteolysis, Uterine Tone and Contraction, Ovulation | Ovulation, Corpus Luteum Secretion of Progesterone | Facilitates Ovarian Production of Progesterone | Formation of Accessory Corpora Lutea | Mammary Stimulation |