Difference between revisions of "Sperm in the Female Tract - Anatomy & Physiology"
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+ | {{toplink | ||
+ | |backcolour =EED2EE | ||
+ | |linkpage =Reproductive System - Anatomy & Physiology | ||
+ | |linktext =Reproductive System | ||
+ | |maplink = Reproductive System (Content Map) - Anatomy & Physiology | ||
+ | |pagetype =Anatomy | ||
+ | |sublink1=Reproductive System - Anatomy & Physiology#Fertilisation.2C Implantation and Early Embryonic Development | ||
+ | |subtext1=FERTILISATION , IMPLANTATION AND EARLY EMBRYONIC DEVELOPMENT''' | ||
+ | }} | ||
+ | <br> | ||
+ | |||
+ | |||
== Overview == | == Overview == | ||
− | * There is immediate retrograde loss at the entrance to the | + | * There is immediate retrograde loss at the entrance to the cervix/uterus with phagocytosis by leukocytes. |
− | * In the | + | * In the cervix, sperm must travel through privileged pathways. This serves to eliminate non-motile sprem and remove some abnormalities. |
− | * In the | + | * In the Uterus, capacitation is initiated with some phagocytosis occuring. |
− | * In the | + | * In the Oviduct, capacitation is completed and sperm show hyperactive motility. |
− | + | * At the Uterotubal Junction, the acrosome reaction occurs and the spermatozoon penetrated the oocyte in fertilization with the formation of male and female pronuclei. | |
− | * At the | ||
== Capacitation== | == Capacitation== | ||
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== Privileged Pathways == | == Privileged Pathways == | ||
− | * Sperm must travel through the highly convoluted | + | * Sperm must travel through the highly convoluted cervix. |
− | * During oestrus, the | + | * During oestrus, the cervix produces mucus. |
** '''Sialomucin''': Low viscosity mucus produced by basal areas of cervical crypts. | ** '''Sialomucin''': Low viscosity mucus produced by basal areas of cervical crypts. | ||
** '''Sulfomucin''': More viscous mucus produced in apical portions of the cervical epithelium covering the tips of cervical folds. | ** '''Sulfomucin''': More viscous mucus produced in apical portions of the cervical epithelium covering the tips of cervical folds. | ||
− | * The difference in viscosity of the mucus creates two distinct environments within the | + | * The difference in viscosity of the mucus creates two distinct environments within the cervix. |
* Sperm encountering sulfomucin are washed out of the tract. | * Sperm encountering sulfomucin are washed out of the tract. | ||
− | * Sperm encountering sialomucin swim into it, creating 'privileged pathways' in deeper cervical crypts. Sperm then traverse the | + | * Sperm encountering sialomucin swim into it, creating 'privileged pathways' in deeper cervical crypts. Sperm then traverse the cervix through these pathways. |
− | * Thus, the | + | * Thus, the cervix acts as a filter to immotile sperm because in order to survive; the sperm must actively swim into the 'privileged pathways'. |
== Hyperactivation == | == Hyperactivation == | ||
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== Acrosome Reaction == | == Acrosome Reaction == | ||
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Revision as of 07:57, 8 September 2008
|
Overview
- There is immediate retrograde loss at the entrance to the cervix/uterus with phagocytosis by leukocytes.
- In the cervix, sperm must travel through privileged pathways. This serves to eliminate non-motile sprem and remove some abnormalities.
- In the Uterus, capacitation is initiated with some phagocytosis occuring.
- In the Oviduct, capacitation is completed and sperm show hyperactive motility.
- At the Uterotubal Junction, the acrosome reaction occurs and the spermatozoon penetrated the oocyte in fertilization with the formation of male and female pronuclei.
Capacitation
Privileged Pathways
- Sperm must travel through the highly convoluted cervix.
- During oestrus, the cervix produces mucus.
- Sialomucin: Low viscosity mucus produced by basal areas of cervical crypts.
- Sulfomucin: More viscous mucus produced in apical portions of the cervical epithelium covering the tips of cervical folds.
- The difference in viscosity of the mucus creates two distinct environments within the cervix.
- Sperm encountering sulfomucin are washed out of the tract.
- Sperm encountering sialomucin swim into it, creating 'privileged pathways' in deeper cervical crypts. Sperm then traverse the cervix through these pathways.
- Thus, the cervix acts as a filter to immotile sperm because in order to survive; the sperm must actively swim into the 'privileged pathways'.