Difference between revisions of "Caprine Arthritis Encephalitis Virus"

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(New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Retroviridae |subtext1=RETROVIRIDAE |pagetype =Bugs }} <br> ====Antigenicity==== *Serologically related to [[Visn...)
 
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*T cells induce immune complex disease
 
*T cells induce immune complex disease
 
*Causes '''encephalitis of kids''' or '''insidious polyarthritis of adults'''
 
*Causes '''encephalitis of kids''' or '''insidious polyarthritis of adults'''
 +
*Also causes [[Respiratory Viral Infections - Pathology#Caprine Arthritis-Encephalitis (CAE)|pneumonia]]
  
 
====Epidemiology====
 
====Epidemiology====

Revision as of 20:09, 20 October 2008



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VIRUSES
RETROVIRIDAE



Antigenicity

  • Serologically related to Visna-Maedi with antigenic and genetic envelope differences

Hosts

  • Goats

Pathogenesis

  • T cells induce immune complex disease
  • Causes encephalitis of kids or insidious polyarthritis of adults
  • Also causes pneumonia

Epidemiology

  • Transfer via milk and colostrum, particularly batch-mixing
  • Present in 10% of UK herds
  • Clinical disease is rare

Diagnosis

  • Visna-Maedi serology (ELISA) test can be used to remove positive stock

Control

  • Separate kids from virus positive mothers at birth
  • Treat mother's colostrum (56 deg for 1 hour)
  • Rear on artificial milk