Changes

==Spectrum of Activity==

==Spectrum of Activity==

Over the years different sub-groups of Penicillins have been developed; this is because many bacteria have developed '''beta-lactamases''' which will therefore reduce the action of the antiobiotic

Over the years different sub-groups of Penicillins have been developed; this is because many bacteria have developed '''beta-lactamases''' which will therefore reduce the action of the antibiotic.

'''Natural Penicillins''' - benzylpenicillin or Penicillin G

'''Natural Penicillins''' - benzylpenicillin or Penicillin G

If a beta-lactamase inhibitor ('''Clavulanic acid''') is added to the drug formulation, the spectrum of most sub-groups is extended.

If a beta-lactamase inhibitor ('''Clavulanic acid''') is added to the drug formulation, the spectrum of most sub-groups is extended.

==Pharmacokinetic Considerations==

==Pharmacokinetic Considerations==