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===Clinical infections===
===[[Respiratory Bacterial Infections - Pathology#Contagious bovine pleuropneumonia (CBPP)|Contagious bovine pleuropneumonia]]===
*[[Respiratory Bacterial Infections - Pathology#Contagious bovine pleuropneumonia (CBPP)|Contagious bovine pleuropneumonia]] is caused by ''M. mycoides'' subsp. ''mycoides''
*A severe contagious disease of cattle
*Endemic in Africa, the Middle East and Asia
*Aerosol transmission by close contact with clinically or subclinically affected animals
*Severity depends on strain and host susceptibility
*Slow spread of infection
*50% morbidity; mortality rate high in severe outbreaks
*Clinical signs
**Acute onset fever, anorexia, depression, lowered milk yield, hyperpnoea, coughing and a mucopurulent nasal discharge
**Dyspnoea occurs with abducted elbows and extended necks and an expiratory grunt
**Can be fatal within 1-3 weeks
**Calves may suffer from [[Joints Inflammatory - Pathology#In Cattle|arthritis]], synovitis and endocarditis
*Gross pathology
**Marbled appearance to lungs with consolidated grey and red lobules separated by emphysematous areas
**Serofibrinous pleural fluid
**Necrotic foci surrounded by fibrous capsules in chronic cases act as source of infection
*Diagnosis
**Clinical signs and post-mortem appearance
**PCR on pleural fluid, lung tissue, regional lymph nodes or bronchoalveolar lavage fluid
**Fluorescent antibody test
**Serological tests such as serum agglutination, haemagglutination, complement fixation, ELISA
*Treatment and control
**Slaughter of affected cattle in counries where the disease is exotic
**Movement restrictions, quaranteen and slaughter of carrier animals in endemic countries
**Vaccination in endemic regions
===''Mycoplasma bovis''===
*Causes severe pneumonia in calves as a primary pathogen
*Can occur secondarily to ''Pasteurella'' and ''Mannheimia'' and [[Respiratory Viral Infections - Pathology#In Cattle|IBR]]
*Associated with [[Joints Inflammatory - Pathology#In Cattle|arthritis]] and mastitis
*Mastitis associated with a severe drop in milk yield and a purulent discharge
===Contagious agalactia of sheep and goats===
*Severe febrile disease of sheep and goats in parts of Europe, Africa, Asia
*Caused by ''M. agalactiae''
*Mastitis, arthritis and conjunctivitis following parturition
*Causes abortion
*Fatal pneumonia in young animals
*Shed in milk; localised in supramammary lymph nodes
*Inactivated, attenuated vaccines available
===Contagious caprine pleuropneumonia===
*Cause [[Peritoneal Cavity Inflammatory - Pathology#In sheep|peritonitis in sheep]] and [[Peritoneal Cavity Inflammatory - Pathology#In goats|peritonitis in goats]] and [[Peritoneal Cavity Inflammatory - Pathology#In pigs|peritonitis in pigs]]
*Cause [[Peritoneal Cavity Inflammatory - Pathology#In sheep|peritonitis in sheep]] and [[Peritoneal Cavity Inflammatory - Pathology#In goats|peritonitis in goats]] and [[Peritoneal Cavity Inflammatory - Pathology#In pigs|peritonitis in pigs]]
*[[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of pigs|Enzootic pneumonia of pigs]] caused by ''M. hyopneumoniae'' and ''M. hyorhinis''
*[[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of pigs|Enzootic pneumonia of pigs]] caused by ''M. hyopneumoniae'' and ''M. hyorhinis''
*''M. bovis'', ''M. dispar'' and ''Ureaplasma'' in [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]
*''M. bovis'', ''M. dispar'' and ''Ureaplasma'' in [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]
* May cause [[General Pathology - Chronic Inflammation#Lymphocytic Inflammation|lymphocytic chronic inflammation]] (peribronchiolar and perialveolar cuffing).
* May cause [[General Pathology - Chronic Inflammation#Lymphocytic Inflammation|lymphocytic chronic inflammation]] (peribronchiolar and perialveolar cuffing).
*''M. ovipneumoniae'' in [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of lambs|enzootic pneumonia of lambs]]
*''M. ovipneumoniae'' in [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of lambs|enzootic pneumonia of lambs]]
*''M. hyosynovia'' and ''M. hyorhinis'' produce syndrome similar to [[Haemophilus species|Glasser's disease]] with milder expression, menigitis rare, [[Joints Inflammatory - Pathology#In Pigs|arthritis]] most consistent
*''M. hyosynovia'' and ''M. hyorhinis'' produce syndrome similar to [[Haemophilus species|Glasser's disease]] with milder expression, menigitis rare, [[Joints Inflammatory - Pathology#In Pigs|arthritis]] most consistent