Difference between revisions of "Benzodiazepines"
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(New page: Benzodiazepines are primarily anxiolytics, but do have sedative effects in man and sick animals. They also cause muscle relaxation and are anticonvulsants. ==Mechanism of Action== ==Side...) |
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==Mechanism of Action== | ==Mechanism of Action== | ||
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| + | GABA is an inhibitory neurotransmitter that opens post-synaptic Cl<sup>-</sup> channel to hyperpolarise the membrane and reduce the chance of action potential conduction occuring. Benzodiazepines modulate the GABA/Cl<sup>-</sup> channel complexes to enhance the effects of GABA. Benzodiazepines therefore have no intrinsic activity. | ||
==Side Effects and Contraindications== | ==Side Effects and Contraindications== | ||
==Drugs in this Group== | ==Drugs in this Group== | ||
Revision as of 15:17, 3 March 2009
Benzodiazepines are primarily anxiolytics, but do have sedative effects in man and sick animals. They also cause muscle relaxation and are anticonvulsants.
Mechanism of Action
GABA is an inhibitory neurotransmitter that opens post-synaptic Cl- channel to hyperpolarise the membrane and reduce the chance of action potential conduction occuring. Benzodiazepines modulate the GABA/Cl- channel complexes to enhance the effects of GABA. Benzodiazepines therefore have no intrinsic activity.