Difference between revisions of "Peritonitis - Cats and Dogs"

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==Description==
 
==Description==
Peritonitis is defined as the inflammation of the peritoneum.  Peritonitis can be septic or non-septic.  Septic peritonitis results from free bacteria in the peritoneal cavity, caused by perforating injuries to the gastrointestnal tract due to foreign bodies, necrosis secondary to obstruction or intussusception.  Non-septic, also known as chemical peritonitis, may be the result of leakage of bile, urine or pancreatic enzymes.  However, non-septic peritonitis can cause septic peritonitis, for example cases where septic urine is present.
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'''Peritonitis''' is defined as the inflammation of the peritoneum, which can be septic or non-septic.  Septic peritonitis results from free bacteria in the peritoneal cavity, caused by perforating injuries to the gastrointestnal tract due to foreign bodies, necrosis secondary to obstruction or intussusception.  Non-septic, also known as chemical peritonitis, may be the result of leakage of bile, urine or pancreatic enzymes.  However, non-septic peritonitis can cause septic peritonitis, for example cases where septic urine is present.
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Peritonitis is a multifactorial disease and the consequence if fatal in most cases.
  
  
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===Fluid therapy===
 
===Fluid therapy===
 
*Aggressive fluid therapy with crystalloid and colloid should be given on initial presentation to improve haemodynamic parameter.
 
*Aggressive fluid therapy with crystalloid and colloid should be given on initial presentation to improve haemodynamic parameter.
*Fluid therapy is also very important in the postoperative period.
+
*Fluid therapy is also very important in the postoperative period.  Both crystalloid and colloid should be continued until the the patient is normotensive.  However, if hypotension continues, a vasopressor such as vasopressin should be considered.
  
 
===Analgesia===
 
===Analgesia===
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===Antimicrobial===
 
===Antimicrobial===
 
*Broad spectrum antibiotics should be given, preferably following culture and sensitivity test.
 
*Broad spectrum antibiotics should be given, preferably following culture and sensitivity test.
 
  
  
 
==Prognosis==
 
==Prognosis==
 
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Guarded.  A rapid diagnosis and treatment improves the prognosis.
  
  

Revision as of 15:44, 18 August 2009



Category:WikiClinical CanineCow
Category:WikiClinical FelineCow


Signalment

Description

Peritonitis is defined as the inflammation of the peritoneum, which can be septic or non-septic. Septic peritonitis results from free bacteria in the peritoneal cavity, caused by perforating injuries to the gastrointestnal tract due to foreign bodies, necrosis secondary to obstruction or intussusception. Non-septic, also known as chemical peritonitis, may be the result of leakage of bile, urine or pancreatic enzymes. However, non-septic peritonitis can cause septic peritonitis, for example cases where septic urine is present.

Peritonitis is a multifactorial disease and the consequence if fatal in most cases.


Diagnosis

Clinical Signs

  • Depressed
  • Tachycardia
  • Tachypnoea
  • Pale, cyanotic or muddly mucous membranes
  • Hypothermia or hyperthermia
  • Abdominal pain


Laboratory Tests

Haematology

  • Significant leucocytosis or leucopaenia

Biochemistry

  • Hypoglycaemia
  • Increased lactate concentration


Diagnostic Imaging

Radiography

  • Abdominal radiography may reveal free gas in the abdomen. This is highly suggestive of peritonitis
  • Thoracic radiograph should be assessed for signs of metastatic disease.


Histopathology

  • Abdominal fluid collected for laboartory analysis via abdominocentesis. The fluid should be stained for intracellular bacteria and assessed for:
    • amylase and lipase for pancreatitis
    • bile for biliary leak
    • creatinine for urine
    • glucose (2.8 mmol/l) and lactate (>5.5 mmol/l) for sepsis

Treatment

It is vital to identify cases which require emergency surgical intervention. Any of the following is a major indication:

  • positive for intracellular bacteria.
  • free gas visible in the abdominal radiograph.
  • presence of penetrating injuries in the abdomen.

Fluid therapy

  • Aggressive fluid therapy with crystalloid and colloid should be given on initial presentation to improve haemodynamic parameter.
  • Fluid therapy is also very important in the postoperative period. Both crystalloid and colloid should be continued until the the patient is normotensive. However, if hypotension continues, a vasopressor such as vasopressin should be considered.

Analgesia

  • Opiods should be given.

Antimicrobial

  • Broad spectrum antibiotics should be given, preferably following culture and sensitivity test.


Prognosis

Guarded. A rapid diagnosis and treatment improves the prognosis.


References

  • Ettinger, S.J. and Feldman, E. C. (2000) Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2 (Fifth Edition) W.B. Saunders Company.
  • Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition) BSAVA
  • Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier.