Difference between revisions of "Neospora"

Revision as of 22:50, 9 April 2010

2 main species
- Neospora caninum in the dog
- Neospora hughesi in the horse

Often misdiagnosed as Toxoplasma gondii
- Sarcocystis cysts have thicker walls

Infection diagnosed by IFAT, ELISA or PCR
- Identification of lesions and organisms in tissue using immunohistochemical staining
- Eliminate other causes of abortion first

Life cycle

Limited range of warm-blooded intermediate hosts
- Asexual reproduction occurs in intermediate host forming tissue cysts

Host range of sexual stage is unknown for N.caninum
- Intermediate host for N.hughesi is the horse, but the definitive host is unknown

Final host
- Dogs pass oocysts
- Role not fully understood in pathogenesis
- 5 day prepatent period
- Other wild canids may also act as final definitive hosts

Intermediate host
- Mostly cattle
- Natural infection has been documented in other herbivores

Transmission
- Transplacental infection occurs in all intermediate hosts and in the canine final host
  - Transplacental transmission can occur in successive pregnancies
- In cattle, vertical transmission occurs
  - Post-natal infection occurs but is less common

Pathogenesis

Dog Neosporosis

@@ Line 41: / Line 41: @@
 ***Post-natal infection occurs but is less common
-*''Neospora caninum'' in [[Parasitic Myositis#Protozoa|myositis]]
+*''Neospora caninum'' in [[Muscles Inflammatory - Pathology#Protozoa|myositis]]
@@ Line 54: / Line 54: @@
 </big>
-*''N. caninum''
-**Necrotising inflammation of muscles
-**Myositis more severe than in toxoplasmosis
-''N. caninum'' - A disease of cattle with late abortion of mummified or autolysed foetus. May also get foetal malformation, e.g. arthrogryposis.
-==Test yourself with the Tissue Cyst Forming Coccidian Flashcards==
-[[Tissue_Cyst_Forming_Coccidian_Flashcards|Tissue Cyst Forming Coccidian Flashcards]]
 [[Category:Tissue Cyst Forming Coccidia]]
-[[Category:To_Do_-_Parasites]]