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| − | ==Coccidioidomycosis==
| + | [[Coccidioidomycosis]] |
| − | [[Image:Coccidioidomycosis.jpg|thumb|right|200px|Coccidioidomycosis spherule histopathology - Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]] | |
| − | *''Coccidioides immitis''
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| − | *Ocurs in the soil
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| − | **Respiratory infections
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| − | **Most commonly seen following dust storms
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| − | *Occurs in arid regions
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| − | **E.g. South West USA and Mexico
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| − | *Non-contageous, systemic mycosis
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| − | *Affects dogs, cattle, sheep and humans
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| − | *Mainly affects the [[Lungs - Anatomy & Physiology|lungs]]
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| − | **Dissemination can occur to other organs
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| − | *Causes nodule or granuloma formation
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| − | **Localised
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| − | **Gross lesions resemble [[Mycobacteria spp.#Bovine tuberculosis|Tb]] in cattle as are usually seen in the bronchial and mediastinal [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and occasionally [[Lungs - Anatomy & Physiology|lungs]]
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| − | **Dissemination can occur, especially in primates and dogs, to the [[Lungs - Anatomy & Physiology|lungs]], [[Liver - Anatomy & Physiology|liver]], [[Spleen - Anatomy & Physiology|spleen]], [[Nervous and Special Senses - Anatomy & Physiology#Central Nervous System (CNS)|brain]] and [[Bones and Cartilage - Anatomy & Physiology|bones]]
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| − | *Thick-walled spherules in tissue
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| − | **Large sporangia burst leaving 'ghost' spherules
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| − | *Saprophytic phase consists of coarse, septate, branching hyphae which fragment into thick-walled, barrel-shaped arthrospores which alternate with empty cells
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| − | **Stained by Lactose Phenol Cotton Blue
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| − | *Grows on Sabouraud's Dextrose agar and Blood agar
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| − | **Flat, moist colonies which develop a coarse, cotton-like aerial mycelium which varies from white to brown in colour
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| − | *Complement fixation test, latex agglutination and immunodiffusion tests can all be used
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| − | **A positive skin test indicates exposure
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| | ==Entomophthoromycisus== | | ==Entomophthoromycisus== |