Difference between revisions of "Dichelobacter nodosus"
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| − | + | *Formerly known as ''Bacteroides'' | |
| − | + | *Characteristics: | |
| − | + | **Large Gram negative rods with terminal swellings | |
| − | + | **Long polar fimbriae | |
| − | + | **16 antigenic types of fimbriae - used to differentiate strains antigenically | |
| − | + | **All strains possess same O antigen | |
| − | + | **Colonies of virulent strains have a dark central zone, a pale granular middle zone and an irregular periphery | |
| − | + | **Strains detected by ELISA and PCR | |
| − | + | **Thermostable proteases and elastase contribute to pathogenesis | |
| − | + | **Keratinolytic proteases required for virulence | |
| − | + | **Fimbriae required for adhesion to hoof | |
| − | + | **Primary pathogen of epidermal tissues of hoof of ruminants, suriving briefly in the envionment | |
| − | + | **Passed from animal to animal | |
| − | + | **Causes foot rot in sheep along with other bacteria | |
| − | Colonies of virulent strains have a dark central zone, a pale granular middle zone and an irregular periphery | + | *Ovine footrot: |
| − | + | **Contagious, economically important disease | |
| − | + | **Wet pasture and hydrated stratum corneum leads to colonisation by Gram positive cocci and [[Arcanobacter pyogenes|''Arcanobacter pyogenes'']], followed by ''F. necrophorum''; addition of ''D. nodosus'' causes footrot | |
| − | Thermostable proteases and elastase contribute to | + | **Can lead to loss of hoof |
| − | + | *Immunity: | |
| − | + | **Homologous antibody to fimbrial antigen prevents adhesion and protects against footrot | |
| − | + | **Antibody must penetrate the epidermal layers and reach adequate concentration on the skin surface | |
| − | + | **Vaccine available | |
| − | + | [[Category:Pathogenic_anaerobic_non-spore-forming_Gram-negative]][[Category:Sheep]] | |
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Revision as of 14:15, 12 May 2010
- Formerly known as Bacteroides
- Characteristics:
- Large Gram negative rods with terminal swellings
- Long polar fimbriae
- 16 antigenic types of fimbriae - used to differentiate strains antigenically
- All strains possess same O antigen
- Colonies of virulent strains have a dark central zone, a pale granular middle zone and an irregular periphery
- Strains detected by ELISA and PCR
- Thermostable proteases and elastase contribute to pathogenesis
- Keratinolytic proteases required for virulence
- Fimbriae required for adhesion to hoof
- Primary pathogen of epidermal tissues of hoof of ruminants, suriving briefly in the envionment
- Passed from animal to animal
- Causes foot rot in sheep along with other bacteria
- Ovine footrot:
- Contagious, economically important disease
- Wet pasture and hydrated stratum corneum leads to colonisation by Gram positive cocci and Arcanobacter pyogenes, followed by F. necrophorum; addition of D. nodosus causes footrot
- Can lead to loss of hoof
- Immunity:
- Homologous antibody to fimbrial antigen prevents adhesion and protects against footrot
- Antibody must penetrate the epidermal layers and reach adequate concentration on the skin surface
- Vaccine available