Difference between revisions of "Bordetella bronchiseptica"
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===Atrophic Rhinitis=== | ===Atrophic Rhinitis=== | ||
| − | *''B. bronchiseptica'' causes [[Nasal Cavity Inflammatory - Pathology#Bacterial rhinitis|Atrophic rhinitis of pigs]] in association with [[Pasteurella | + | *''B. bronchiseptica'' causes [[Nasal Cavity Inflammatory - Pathology#Bacterial rhinitis|Atrophic rhinitis of pigs]] in association with [[Pasteurella multocida|''Pasteurella multocida'']] |
*Colonises nasopharynx | *Colonises nasopharynx | ||
*Infection must occur during first few weeks of life | *Infection must occur during first few weeks of life | ||
*Produces dermonecrotic toxin which damages osteoblasts, preventing bone formation | *Produces dermonecrotic toxin which damages osteoblasts, preventing bone formation | ||
*Leads to turbinate atrophy without distortion of the snout in uncomplicated infections | *Leads to turbinate atrophy without distortion of the snout in uncomplicated infections | ||
| − | *[[Nasal Cavity Inflammatory - Pathology#Bacterial rhinitis|Atrophic rhinitis]] results when [[Pasteurella | + | *[[Nasal Cavity Inflammatory - Pathology#Bacterial rhinitis|Atrophic rhinitis]] results when [[Pasteurella multocida|''Pasteurella multocida'']] colonises and produces osteolytic toxin, leading to bone resorption |
*Malformation of snout in growing pigs as well as poor growth | *Malformation of snout in growing pigs as well as poor growth | ||
*increases with high stocking density and poor ventilation | *increases with high stocking density and poor ventilation | ||
*Vaccine available | *Vaccine available | ||
[[Category:Bordetella species]][[Category:Dog]][[Category:Pig]] | [[Category:Bordetella species]][[Category:Dog]][[Category:Pig]] | ||
Revision as of 12:46, 14 May 2010
Infectious canine tracheitis/Kennel cough
- B. bronchiseptica acts as a primary pathogen in Infectious canine tracheitis
- Frequently isolated from dogs with respiratory disease
- Often found with viruses or mycoplasma
- Adheres to ciliated epithelial cells in the trachea
- Colonisation and proliferation in trachea
- Releases toxins causing epithelial necrosis and prevents ciliary clearance
- Irritation to tract causes coughing
- Mortality rates low
- Peribronchial inflammation and bronchopneumonia
can result in unvaccinated puppies or immunosuppressed dogs
- Severe pneumonia following secondary infection e.g. with Streptococci
- Fatal bronchopneumonia if occurs secondary to canine distemper virus
- Transmission via respiratory secretions by direct contact or aerosol and on fomites
- Clinical signs:
- Develop within 3-4 days; persist for up to 2 weeks
- Coughing
- Gagging
- Mild serous oculonasal discharge
- Treatments includes antibiotics if coughing persists or bronchopneumonia develops
- Live intranasal vaccines
- Also found in respiratory tract of cats; can cause pneumonia in kittens; vaccine available
Atrophic Rhinitis
- B. bronchiseptica causes Atrophic rhinitis of pigs in association with Pasteurella multocida
- Colonises nasopharynx
- Infection must occur during first few weeks of life
- Produces dermonecrotic toxin which damages osteoblasts, preventing bone formation
- Leads to turbinate atrophy without distortion of the snout in uncomplicated infections
- Atrophic rhinitis results when Pasteurella multocida colonises and produces osteolytic toxin, leading to bone resorption
- Malformation of snout in growing pigs as well as poor growth
- increases with high stocking density and poor ventilation
- Vaccine available