Difference between revisions of "Microsporidia"
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*Infect a wide range of fish and animals | *Infect a wide range of fish and animals | ||
**Including humans | **Including humans | ||
| − | ***Causes severe [[Diarrhoea|diarrhoea]] in immunocompromised patients | + | ***Causes severe [[Intestine Diarrhoea - Pathology|diarrhoea]] in immunocompromised patients |
*Intracellular parasites | *Intracellular parasites | ||
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**Raise foodbowls and water bottles off ground | **Raise foodbowls and water bottles off ground | ||
**Do not use tiered hutches | **Do not use tiered hutches | ||
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[[Category:Miscellaneous_Protozoa]] | [[Category:Miscellaneous_Protozoa]] | ||
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Revision as of 18:51, 18 May 2010
- Infect a wide range of fish and animals
- Including humans
- Causes severe diarrhoea in immunocompromised patients
- Including humans
- Intracellular parasites
- Produce resistant spores
- Mature organism
- Contains a polar filament (coiled tube)
- Encephalitozoon cuniculi
- Found particularly in laboratory and pet rabbits
Life Cycle
- Spores are ingested
- Infects mucosal cells
- Polar filament pushed through the host cell walls
- Contents of the spore enter the host cell and multiply
- Differentiates into spores
- Spreads to target organs
- Infects macrophages
- Spores infect other host cells or are passed out via the faeces, urine or respiratory secretions
Pathogenesis
- Cells rupture
- Causes a granulomata in target organ
- Chronic disease
Diagnosis
- Clinical signs
- Head tilt, incontinence, uveitis, cataracts
- In most cases is asymptomatic
- Serology
- ELISA
- Post-mortem
- Granuloma
Control and Treatment
- Fenbendazole licensed for use in rabbits
- Cull seropositive animals
- Strict hygiene
- Raise foodbowls and water bottles off ground
- Do not use tiered hutches