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− | {{unfinished}} | + | {{frontpage |
| + | |pagetitle =Rhabdoviridae |
| + | |pagebody =<div style="text-align: left; direction: ltr; margin-left: 1em;"> |
| + | [[Rabies]] is a neurological killer that has evolved a fool-proof technique of transmission, and it cleverly evades the species barrier to present a potent threat to mammalian life. While the simplicity of the virus ensures its transmission, it also contributes to its weakness: its monoclonal antigenicity means that a single vaccination covers all strains of the disease. Though rabies is considered endemic in parts of the developed and undeveloped world, vaccination schemes have rendered the disease controllable to a satisfactory degree. Nonetheless, infection is still largely fatal and the disease should not be taken lightly. |
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− | =Introduction= | + | <categorytree mode=pages>Rhabdoviridae</categorytree> |
− | [[Rabies]] is a neurological killer that has evolved a fool-proof technique of transmission, and it cleverly evades the species barrier to present a potent threat to mammalian life. While the simplicity of the virus ensures its transmission, it also contributes to its weakness: its monoclonal antigenicity means that a single vaccination covers all strains of the disease. Though rabies is considered endemic in parts of the developed and undeveloped world, vaccination schemes have rendered the disease controllable to a satisfactory degree. Nonetheless, infection is still largely fatal and the disease should not be taken lightly.
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− | =Morphology= | + | ==Morphology== |
| *Large, enveloped, negative-sense RNA virus | | *Large, enveloped, negative-sense RNA virus |
| *'''Bullet-shaped''' with short glycoprotein spikes | | *'''Bullet-shaped''' with short glycoprotein spikes |
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− | =Types and Subtypes= | + | ==Types and Subtypes== |
| Two Genera: | | Two Genera: |
| #Lyssaviruses: 7 genotypes | | #Lyssaviruses: 7 genotypes |
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| ##Fish Rhabdoviruses, such as viral hemorrhagic syndrome and infectious haematopoetic necrosis virus | | ##Fish Rhabdoviruses, such as viral hemorrhagic syndrome and infectious haematopoetic necrosis virus |
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− | =Virulence and Pathogenesis= | + | ==Virulence and Pathogenesis== |
| *Rabies is moderately resistant: it can survive well in dark places at low temperatures for several days | | *Rabies is moderately resistant: it can survive well in dark places at low temperatures for several days |
| *Infection occurs through a '''penetrating bite''' in which virus is transmitted via '''saliva''' | | *Infection occurs through a '''penetrating bite''' in which virus is transmitted via '''saliva''' |