Difference between revisions of "Category:Hepatoxicity, Acute"

Acute hepatoxicity

Almost invariably causes widespread haemorrhages in the body due to excessive consumption of the clotting factors in the damaged liver coupled with failure to produce these factors by the damaged liver.

Blue-green Algae

Iron

• the use of iron-dextran compounds to combat anaemia
• common in piglets which are deficient in Vitamin E
• produces massive necrosis in the liver

Cresols

• from tarred piggeries and clay pigeons
• produce massive necrosis in the liver of pigs

Clinical

• jaundice
• weakness
• coma
• death

NB: former use of carbon tetrachloride as an anthelmintic and phosphorous as a rodenticide has produced liver necrosis