Difference between revisions of "Carcinoma"
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==Primary Liver Tumours== | ==Primary Liver Tumours== | ||
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===Hepatocytic=== | ===Hepatocytic=== | ||
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*more in dogs and cats | *more in dogs and cats | ||
=====Gross===== | =====Gross===== | ||
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*can be very variable appearing as sheets or cords of neoplastic cells | *can be very variable appearing as sheets or cords of neoplastic cells | ||
*cells generally smaller with a higher nucleus to cytoplasmic ratio | *cells generally smaller with a higher nucleus to cytoplasmic ratio | ||
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===Cholangiocellular - bile duct=== | ===Cholangiocellular - bile duct=== | ||
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*ductal and acinar proliferation in abundant fibrous tissue | *ductal and acinar proliferation in abundant fibrous tissue | ||
*sometimes papillary formations | *sometimes papillary formations | ||
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==Secondary Liver Tumours== | ==Secondary Liver Tumours== | ||
*from a variety of origins | *from a variety of origins | ||
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[[Category:Liver,_Primary_Tumours]] | [[Category:Liver,_Primary_Tumours]] | ||
[[Category:Liver,_Secondary_Tumours]] | [[Category:Liver,_Secondary_Tumours]] | ||
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Revision as of 14:45, 8 June 2010
Primary Liver Tumours
Hepatocytic
- more in dogs and cats
Gross
- can be difficult to distinguish grossly from adenomas
- usually one single large mass and additional smaller masses (intrahepatic metastases)
- may have features of malignancy such as internal necrosis and haemorrhage
Microscopically
- can be very variable appearing as sheets or cords of neoplastic cells
- cells generally smaller with a higher nucleus to cytoplasmic ratio
Cholangiocellular - bile duct
- more common than adenoma
- reported in all species (mostly dogs and cats)
Gross
- usually multiple whitish umbilicated nodules that are present diffusely throughout the liver
- actually look as though they were secondary tumours
- firm on cut surface
- due to fibrosis
Microscopically
- distinctly adenocarcinomatous
- ductal and acinar proliferation in abundant fibrous tissue
- sometimes papillary formations
Secondary Liver Tumours
- from a variety of origins