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| ==Signalment and Description== | | ==Signalment and Description== |
− | ===Hepatocellular Tumours ([[Liver Proliferative - Pathology #Hepatocytic|Hepatocellular carcinomas]] (HCC) and [[Liver Proliferative - Pathology #Hepatocytic|Hepatomas]])=== | + | ===Hepatocellular Tumours ([[Carcinoma#Hepatocytic|Hepatocellular carcinomas]] (HCC) and [[Adenoma#Hepatocytic|Hepatomas]])=== |
| * HCC occurs more frequently in dogs and hepatomas more commonly in cats. They are the most common primary liver tumour in dogs and the second most common in cats. | | * HCC occurs more frequently in dogs and hepatomas more commonly in cats. They are the most common primary liver tumour in dogs and the second most common in cats. |
| * Male dogs over 10 years old are the most frequently affected by HCC and Miniature schnauzers may have a breed predisposition. | | * Male dogs over 10 years old are the most frequently affected by HCC and Miniature schnauzers may have a breed predisposition. |
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| * Metastatic rate for dogs with massive HCC: 0-37% | | * Metastatic rate for dogs with massive HCC: 0-37% |
| * Metastatic rate for dogs with nodular and diffuse HCC: 93-100% | | * Metastatic rate for dogs with nodular and diffuse HCC: 93-100% |
− | * [[Liver Proliferative - Pathology #Hepatocytic|Hepatomas]]) are usually incidental findings and non-significant | + | * [[Adenoma#Hepatocytic|Hepatomas]]) are usually incidental findings and non-significant |
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| ===Cholangiocellular Tumours (Bile duct carcinomas and adenomas)=== | | ===Cholangiocellular Tumours (Bile duct carcinomas and adenomas)=== |
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| * Primary tumours are aggressive and often affect more than one liver lobe and metastasise most frequently to the regional lymph nodes, the lungs and peritoneum. | | * Primary tumours are aggressive and often affect more than one liver lobe and metastasise most frequently to the regional lymph nodes, the lungs and peritoneum. |
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− | ===Sarcomas ([[Liver Proliferative - Pathology #Haemangiosarcoma|Haemangiosarcoma]] (HSA), Leiomyosarcoma, Fibrosarcoma)=== | + | ===Sarcomas ([[Haemangiosarcoma|Haemangiosarcoma]] (HSA), Leiomyosarcoma, Fibrosarcoma)=== |
| * HSA is the most common hepatic sarcoma in cats | | * HSA is the most common hepatic sarcoma in cats |
| * Leiomyosarcoma is the most common hepatic sarcoma in dogs | | * Leiomyosarcoma is the most common hepatic sarcoma in dogs |
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| ==Treatment== | | ==Treatment== |
| ===Surgery=== | | ===Surgery=== |
− | Surgical excision is advised for hepatic adenomas, bile duct adenomas and massive [[Liver Proliferative - Pathology #Hepatocytic|hepatocellular carcinomas]]. Nodulectomy or lobectomy can be used for focal tumours of one or more lobes. Diffuse tumours and widespread nodular disease carry a worse prognosis. | + | Surgical excision is advised for hepatic adenomas, bile duct adenomas and massive [[Carcinoma#Hepatocytic|hepatocellular carcinomas]]. Nodulectomy or lobectomy can be used for focal tumours of one or more lobes. Diffuse tumours and widespread nodular disease carry a worse prognosis. |
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| ===Chemotherapy=== | | ===Chemotherapy=== |
− | Not currently recommended for primary hepatic neoplasia. Some metastatic sarcomas, for example [[Liver Proliferative - Pathology #Haemangiosarcoma|haemangiosarcomas]], may show some response. | + | Not currently recommended for primary hepatic neoplasia. Some metastatic sarcomas, for example [[Haemangiosarcoma|haemangiosarcomas]], may show some response. |
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| ===Radiotherapy=== | | ===Radiotherapy=== |
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| ==Prognosis== | | ==Prognosis== |
− | The mean survival time for massive [[Liver Proliferative - Pathology #Hepatocytic|hepatocellular carcinomas]] following surgery is approximately 1 year. Otherwise the prognosis is poor for other malignant and metastatic tumours. If successfully excised the prognosis for benign tumours is good. | + | The mean survival time for massive [[Carcinoma#Hepatocytic|hepatocellular carcinomas]] following surgery is approximately 1 year. Otherwise the prognosis is poor for other malignant and metastatic tumours. If successfully excised the prognosis for benign tumours is good. |
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