Difference between revisions of "Nocardia asteroides"
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− | *Found in soil and decaying vegetation - saprophytic | + | **Found in soil and decaying vegetation - saprophytic |
− | *Opportunistic infection of immunocompromised animals | + | **Opportunistic infection of immunocompromised animals |
− | *Infection via inhalation, wounds or teat canal; also ingestion | + | **Infection via inhalation, wounds or teat canal; also ingestion |
− | *Causes granulomatous lesions in animals | + | **Causes granulomatous lesions in animals |
− | *Canine nocardiosis: | + | **Canine nocardiosis: |
− | **Thoracic, [[Bacterial skin infections - Pathology#bacterial granulomatous dermatitis|cutaneous]] and disseminated forms | + | ***Thoracic, [[Bacterial skin infections - Pathology#bacterial granulomatous dermatitis|cutaneous]] and disseminated forms |
− | **Cutaneous pyogranulomas: ulcers or granulomatous swellings with discharging fistulae | + | ***Cutaneous pyogranulomas: ulcers or granulomatous swellings with discharging fistulae |
− | **[[Peritonitis - | + | ***[[Peritonitis - Pathology#In dogs|peritonitis]] |
− | **[[Respiratory Bacterial Infections - Pathology#Nocardiosis|pleuritis]] and pyothorax with fever, anorexia and respiratory distress | + | ***[[Respiratory Bacterial Infections - Pathology#Nocardiosis|pleuritis]] and pyothorax with fever, anorexia and respiratory distress |
− | **Disseminated lesions | + | ***Disseminated lesions |
− | **Treat with appropriate systemic antibiotics for 6 weeks | + | ***Treat with appropriate systemic antibiotics for 6 weeks |
− | *Cattle: chronic mastitis; abortion | + | **Cattle: chronic mastitis; abortion |
− | *Pigs: abortion | + | **Pigs: abortion |
− | *Sheep, goats, horses: wound infections; mastitis; pneumonia | + | **Sheep, goats, horses: wound infections; mastitis; pneumonia |
− | *Survives and multiplies in macrophages | + | **Survives and multiplies in macrophages |
− | *Superoxide dismutase and catalase as well as a thick peptidoglycan wall prevent activity of phagocytes | + | **Superoxide dismutase and catalase as well as a thick peptidoglycan wall prevent activity of phagocytes |
− | *Chronic, progressive disease | + | **Chronic, progressive disease |
− | *Positive modified Ziehl-Neelson | + | **Positive modified Ziehl-Neelson |
− | *Culture on blood agar and incubate under aerobic conditions at 37 degrees centigrade for 10 days | + | **Culture on blood agar and incubate under aerobic conditions at 37 degrees centigrade for 10 days |
− | *White, powdery colonies, adherent to the agar appear after 5 days | + | **White, powdery colonies, adherent to the agar appear after 5 days |
− | *Subculture onto Sabouraud dextrose agar yields wrinkled, orange colonies | + | **Subculture onto Sabouraud dextrose agar yields wrinkled, orange colonies |
− | *Lesions difficult to treat due to resistance of organisms to many antimicrobials (e.g. penicillins) | + | **Lesions difficult to treat due to resistance of organisms to many antimicrobials (e.g. penicillins) |
− | *Cell-mediated immunity required | + | **Cell-mediated immunity required |
− | + | [[Category:Nocardia species]][[Category:Dog]][[Category:Pig]][[Category:Cattle]] | |
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− | [[Category:Nocardia species]][[Category:Dog | ||
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Revision as of 13:29, 10 June 2010
- Found in soil and decaying vegetation - saprophytic
- Opportunistic infection of immunocompromised animals
- Infection via inhalation, wounds or teat canal; also ingestion
- Causes granulomatous lesions in animals
- Canine nocardiosis:
- Thoracic, cutaneous and disseminated forms
- Cutaneous pyogranulomas: ulcers or granulomatous swellings with discharging fistulae
- peritonitis
- pleuritis and pyothorax with fever, anorexia and respiratory distress
- Disseminated lesions
- Treat with appropriate systemic antibiotics for 6 weeks
- Cattle: chronic mastitis; abortion
- Pigs: abortion
- Sheep, goats, horses: wound infections; mastitis; pneumonia
- Survives and multiplies in macrophages
- Superoxide dismutase and catalase as well as a thick peptidoglycan wall prevent activity of phagocytes
- Chronic, progressive disease
- Positive modified Ziehl-Neelson
- Culture on blood agar and incubate under aerobic conditions at 37 degrees centigrade for 10 days
- White, powdery colonies, adherent to the agar appear after 5 days
- Subculture onto Sabouraud dextrose agar yields wrinkled, orange colonies
- Lesions difficult to treat due to resistance of organisms to many antimicrobials (e.g. penicillins)
- Cell-mediated immunity required