Difference between revisions of "Category:Asfarviridae"
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==Virulence and Pathogenesis== | ==Virulence and Pathogenesis== | ||
*Infects either '''upper respiratory tract''' or '''skin''' via '''ticks''' | *Infects either '''upper respiratory tract''' or '''skin''' via '''ticks''' | ||
| − | *Enters bloodstream in [[Monocytes | + | *Enters bloodstream in [[Monocytes|monocytes]] |
*Reaches viscera and bone marrow within days | *Reaches viscera and bone marrow within days | ||
*Induces a '''clotting defect''' and '''hemolysis''' in red blood cells | *Induces a '''clotting defect''' and '''hemolysis''' in red blood cells | ||
Revision as of 12:43, 12 June 2010
Asfarviridae
Asfarviridae receives it's name from African Swine Fever virus, which is derived from any of this family of viruses. ASF is a serious exotic virus that should not be confused with Classical Swine Fever.
Morphology
- Large, enveloped, icosahedral, cytoplasmic DNA virus
Virulence and Pathogenesis
- Infects either upper respiratory tract or skin via ticks
- Enters bloodstream in monocytes
- Reaches viscera and bone marrow within days
- Induces a clotting defect and hemolysis in red blood cells
- Also affects lymphocytes:
- Infects Th cells and causes them not to produce B-stimulating cytokines
- Antigen-stimulated B-cells undergo apoptosis rather than producing antibody
- General cell signal transduction is blocked, decreasing non-specific immunity
Pages in category "Asfarviridae"
This category contains only the following page.