Difference between revisions of "Immunoglobulins Flashcards"
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+ | {{toplink | ||
+ | |linkpage =Immunoglobulins | ||
+ | |linktext =IMMUNOGLOBULINS | ||
+ | |sublink1 =Flash Cards - WikiBlood | ||
+ | |subtext1 =WIKIBLOOD FLASHCARDS | ||
+ | |pagetype =Blood | ||
+ | }} | ||
===Immunoglobulins Structure and Function=== | ===Immunoglobulins Structure and Function=== | ||
<FlashCard questions="8"> | <FlashCard questions="8"> | ||
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*Dogs | *Dogs | ||
*Rodents | *Rodents | ||
− | |l5=Immunoglobulin D#Function | + | |l5=Immunoglobulin D - WikiBlood#Function |
|q6=What is the main function of IgD? | |q6=What is the main function of IgD? | ||
|a6=Helps B cell development | |a6=Helps B cell development | ||
− | |l6=Immunoglobulin D#Function | + | |l6=Immunoglobulin D - WikiBlood#Function |
|q7=True or False: IgE is not a soluble antibody? | |q7=True or False: IgE is not a soluble antibody? | ||
|a7=True | |a7=True | ||
− | |l7=Immunoglobulin E | + | |l7=Immunoglobulin E - WikiBlood |
|q8=What are the functions of IgE? | |q8=What are the functions of IgE? | ||
|a8= | |a8= | ||
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*Involved in type I hypersensitivity reactions | *Involved in type I hypersensitivity reactions | ||
*Involved in producing immunity to parasitic worms and nematode parasites | *Involved in producing immunity to parasitic worms and nematode parasites | ||
− | |l8=Immunoglobulin E#Function | + | |l8=Immunoglobulin E - WikiBlood#Function |
|q9=True or False: IgG is the smallest antibody and can easily leave the plasma and enter tissue? | |q9=True or False: IgG is the smallest antibody and can easily leave the plasma and enter tissue? | ||
|a9=True | |a9=True | ||
− | |l9=Immunoglobulin G | + | |l9=Immunoglobulin G - WikiBlood |
|q10=Where is IgG produced? | |q10=Where is IgG produced? | ||
|a10=Bone marrow | |a10=Bone marrow | ||
*Spleen | *Spleen | ||
*Lymph nodes | *Lymph nodes | ||
− | |l10=Immunoglobulin G#Production | + | |l10=Immunoglobulin G - WikiBlood#Production |
|q11=What is the function of IgG? | |q11=What is the function of IgG? | ||
|a11=Activates the classical pathway of the complement cascade | |a11=Activates the classical pathway of the complement cascade | ||
*Can act as targets for macrophages, eosinophils and [[Neutrophils|neutrophils]] | *Can act as targets for macrophages, eosinophils and [[Neutrophils|neutrophils]] | ||
*Causes agglutination and opsonisation of bacteria | *Causes agglutination and opsonisation of bacteria | ||
− | |l11=Immunoglobulin G#Function | + | |l11=Immunoglobulin G - WikiBlood#Function |
|q12=True or False: IgM is a monomer | |q12=True or False: IgM is a monomer | ||
|a12= | |a12= | ||
*True | *True | ||
*But it is secreted as a pentamer | *But it is secreted as a pentamer | ||
− | |l12=Immunoglobulin M#Structure | + | |l12=Immunoglobulin M - WikiBlood#Structure |
|q13=IgM is five times larger than most other antibodies. What effect does this have on its function? | |q13=IgM is five times larger than most other antibodies. What effect does this have on its function? | ||
|a13= | |a13= | ||
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*Does not diffuse quickly or enter tissues readily | *Does not diffuse quickly or enter tissues readily | ||
*Its concentration in extracellular fluid and lymph is low | *Its concentration in extracellular fluid and lymph is low | ||
− | |l13=Immunoglobulin M#Production | + | |l13=Immunoglobulin M - WikiBlood#Production |
|q14=What are the main functions of IgM? | |q14=What are the main functions of IgM? | ||
|a14= | |a14= | ||
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*Opsonisation | *Opsonisation | ||
*Virus neutralisation | *Virus neutralisation | ||
− | |l14=Immunoglobulin M#Function | + | |l14=Immunoglobulin M - WikiBlood#Function |
</FlashCard> | </FlashCard> | ||
===Immunoglobulins Variation=== | ===Immunoglobulins Variation=== | ||
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|l6=Immunoglobulins#Immunoglobulin Class Switching | |l6=Immunoglobulins#Immunoglobulin Class Switching | ||
</FlashCard> | </FlashCard> | ||
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Revision as of 16:24, 12 June 2010
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Immunoglobulins Structure and Function
Question | Answer | Article | |
What are immunoglobulins also known as? | Antibodies
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Link to Article | |
How many domains does the heavy chain have? |
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Link to Article | |
How many domains does the light chain have? |
|
Link to Article | |
What are hypervariable domains? |
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Link to Article | |
What does Fab stand for and from which chain is it generated? |
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Link to Article | |
What does Fc stand for and from which chain is it generated? |
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Link to Article | |
What does the Fc fragment do? | Mediates phagocytosis
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Link to Article | |
What are the four major effects of antibodies? |
|
Link to Article |
Classes of Immunoglobulin
Question | Answer | Article | |
How do the five classes of immunoglobulins vary from each other? | They each have a different composition to their heavy chains
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Link to Article | |
IgA is specially adapted for function at which type of surface? | Mucosal surfaces
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Link to Article | |
True or False: IgA is a monomer |
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Link to Article | |
What are the functions of IgA? |
|
Link to Article | |
In which species has IgD been identified? |
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Link to Article | |
What is the main function of IgD? | Helps B cell development
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Link to Article | |
True or False: IgE is not a soluble antibody? | True
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Link to Article | |
What are the functions of IgE? |
|
Link to Article | |
True or False: IgG is the smallest antibody and can easily leave the plasma and enter tissue? | True
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Link to Article | |
Where is IgG produced? | Bone marrow
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Link to Article | |
What is the function of IgG? | Activates the classical pathway of the complement cascade
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Link to Article | |
True or False: IgM is a monomer |
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Link to Article | |
IgM is five times larger than most other antibodies. What effect does this have on its function? |
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Link to Article | |
What are the main functions of IgM? |
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Link to Article |
Immunoglobulins Variation
Question | Answer | Article | |
Which genes code for the immunoglobulin subtypes and on which chain are they located? |
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Link to Article | |
Complete the sentences about IgG subtypes:
Humans and rodents have ??? IgG subtypes. Dogs have ??? IgG subtypes. Ruminats have ??? IgG subtypes. |
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Link to Article | |
What are allotypes? |
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Link to Article | |
What are idiotypes? | Variations in the sequences of amino acids in the variable regions of the light and heavy chains
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Link to Article | |
What is immunoglobulin heavy chain switching? |
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Link to Article | |
How do different classes of antibody differ from each other? |
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Link to Article |