Difference between revisions of "Category:Cardiovascular System - Developmental Pathology"

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===Endocardial fibro-elastosis===
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===[[Endocardial fibro-elastosis]]===
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Seen in Burmese kittens.  Collagen and elastin are deposited in the endocardium, limiting its function.  Animals are often found dead at 2-3 months of age.
 
 
[[Category:Cardiovascular System - Pathology]]
 
[[Category:Cardiovascular System - Pathology]]

Revision as of 10:45, 22 June 2010

Cardiovascular System - Developmental Pathology

Congenital abnormalities occur relatively commonly in young (approximately 1% all human births). May produce dramatic clinical signs or signs may be vague, such as failure to thrive. Clinical signs may become more apparent as the animal grows and activity levels increase.

The aetiology of congenital defects of the heart and great vessels are mostly unknown. Possible contributing factors include:

  • Genetic; E.g. Mutation in the ova or sperm or mutation in the zygote.
  • Environmental; Includes infection (usually viral), chemical, nutritional and physical factors.

Understanding the normal development of the heart and great vessels allows an understanding of the morphology and pathology of the congenital abnormalities seen in mammals.





Ectopia Cordis

Endocardial fibro-elastosis