Difference between revisions of "Chlamydophila abortus"
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(Redirected page to Enzootic Abortion of Ewes) |
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− | + | *Ovine enzootic abortion | |
− | + | *Especially in intensive systems | |
− | [[Category:Chlamydophila_species]][[Category:Sheep | + | *Ewe lambs may acquire infection at birth and abort in their first pregnancy |
+ | *Pathogenesis: | ||
+ | **Infection via ingestion or inhalation causes a bacteraemia | ||
+ | **Bacteria localise in placenta and cause placentitis, leading to late abortion or premature weak lambs | ||
+ | **Necrosis of cotyledons and oedema of adjacent tissue, as well as dirty pink uterine discharge | ||
+ | **Aborted lambs well preserved | ||
+ | **Large numbers of chlamydiae shed in placenta and uterine discharges; survive in environment for several days | ||
+ | **Abortion rates may reach 30% in susceptible flock | ||
+ | **Ewes infected late in pregnancy may not abort, but may abort during the next pregnancy | ||
+ | **No other clinical signs in aborting ewes | ||
+ | **Fertility not impaired | ||
+ | *Transmission: | ||
+ | **Survival of elementary bodies in faeces and wild birds are a source of infection from one lambing season to the next | ||
+ | **Ewes may be carriers for several years | ||
+ | **Venereal transmission from infected rams | ||
+ | **Some immunity develops after infection, protecting ewes from subsequent disease | ||
+ | *Vaccination: | ||
+ | **Live attenuated vaccines prior to breeding or inactivated vaccines during pregnancy | ||
+ | **Vaccines prevent infection but will not clear infection from persistently-infected animals | ||
+ | **Vaccination of ewe lambs prior to breeding | ||
+ | *Treatment: long-acting oxytetracyclines during an outbreak to protect in-contact pregnant ewes | ||
+ | *Control: isolate aborted ewes; destroy placentas, thorough cleaning | ||
+ | *Also abortion in cattle, goats and pigs | ||
+ | *Serious infection in pregnant women[[Category:Chlamydophila_species]][[Category:Sheep]][[Category:Cattle]][[Category:Goat]][[Category:Pig]][[Category:Zoonoses]] | ||
+ | [[Category:To_Do_-_Bacteria]] |
Revision as of 10:33, 25 June 2010
- Ovine enzootic abortion
- Especially in intensive systems
- Ewe lambs may acquire infection at birth and abort in their first pregnancy
- Pathogenesis:
- Infection via ingestion or inhalation causes a bacteraemia
- Bacteria localise in placenta and cause placentitis, leading to late abortion or premature weak lambs
- Necrosis of cotyledons and oedema of adjacent tissue, as well as dirty pink uterine discharge
- Aborted lambs well preserved
- Large numbers of chlamydiae shed in placenta and uterine discharges; survive in environment for several days
- Abortion rates may reach 30% in susceptible flock
- Ewes infected late in pregnancy may not abort, but may abort during the next pregnancy
- No other clinical signs in aborting ewes
- Fertility not impaired
- Transmission:
- Survival of elementary bodies in faeces and wild birds are a source of infection from one lambing season to the next
- Ewes may be carriers for several years
- Venereal transmission from infected rams
- Some immunity develops after infection, protecting ewes from subsequent disease
- Vaccination:
- Live attenuated vaccines prior to breeding or inactivated vaccines during pregnancy
- Vaccines prevent infection but will not clear infection from persistently-infected animals
- Vaccination of ewe lambs prior to breeding
- Treatment: long-acting oxytetracyclines during an outbreak to protect in-contact pregnant ewes
- Control: isolate aborted ewes; destroy placentas, thorough cleaning
- Also abortion in cattle, goats and pigs
- Serious infection in pregnant women