Difference between revisions of "Sendai Virus"
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[[Category:Paramyxovirinae]][[Category:Rodents]] | [[Category:Paramyxovirinae]][[Category:Rodents]] | ||
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Revision as of 22:46, 26 June 2010
Murine Parainfluenza - 1 (Sendai Virus)
- Endemic in many mouse colonies
- Most mice show no symptoms due to maternal antibodies
- But minor respiratory lesions may invalidate carcinogenic or toxicological studies
- Immunological studies also confused due to virus activating NK cells via high circulating IF 3-4 days post-infection
- Control achieved by:
- Purchasing specific pathogen free (SPF) mice
- Kill whole colony in an outbreak -> disinfection -> formalin fumigation