Difference between revisions of "Peripheral Odontogenic Fibroma"

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Also known as: ''''' Fibromatous epulis of periodontal ligament — Epulis — Ossifying Epulis
 
 
==Introduction==
 
[[File:Fibrous epulis.JPG|thumb|200px|right|Fibrous epulis]]
 
Peripheral odontogenic fibroma is a benign tumour that arises from the [[Tooth - Anatomy & Physiology#Periodontal Ligament|periodontal ligament]]. It was previously known as a fibromatous epulis and ossifying epulis depending on the degree of mineralization.
 
They present as firm, smooth swellings of the [[Gingiva|gingiva]] and are normally indistinguishable from [[Gingival Hyperplasia|gingival hyperplasia]].
 
  
==Typical Signalment==
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{{dog}}
Most common benign tumour found in the oral cavity in dogs but is less common in cats. Is seen in dogs of any age but more common in those older than 6 years. .
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{{cat}}
  
==Clinical Signs==
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Epulis
Include halitosis, oral bleeding, dental disruption or loss, facial or mandibular deformity, excessive salivation, growth protruding from the mouth and rarely dysphagia.
 
  
==Diagnostic Imaging==
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==Typical Signalment==
Radiographs are required to differentiate this benign neoplasm from malignant or locally aggressive lesions. Intra-oral radiographs will evaluate the oral lesion itself and thoracic radiography to evaluate for metastasies (if a malignancy is a diagnostic possibility). Radiographs typically show a soft tissue opacity in the the gingiva region with varying degrees of mineralization. Bone involvement is not a feature of this neoplasm and hence is not to be confused with [[Acanthomatous Ameloblastoma|Acanthomatous Ameloblastoma]] which often invades bone.
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*Most common benign tumour found in the oral cavity in dogs
 
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*Less common in cats
Radiography cannot be used to differentiate a peripheral odontogenic fibroma from a hyperplastic gingival lesion.
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*Seen in dogs of any age but more common in those > 6years old
 
+
==Description==
==Biopsy==
+
Peripheral odontogenic fibroma is a benign tumour that arises from the [[Periodontal ligament - Anatomy & Physiology|periodontal ligament]]. It was previously known as a fibromatous epulis and ossifying epulis depending on the degree of mineralization.  
An incisional biopsy is required to obtain a definitive diagnosis.
+
They present as firm, smooth swellings of the [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|gingiva]] and are normally indistinguishable from [[Gingival Hyperplasia|gingival hyperplasia]].
 +
==Diagnosis==
  
==Pathology==
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===Clinical Signs===
[[Image:epulis.gif|right|thumb|200px|<small><center>Canine Epulis(Courtesy of Alun Williams (RVC))</center></small>]]
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*halitosis
Proliferation of fibrous tissue with a variety of osteoid, [[Tooth - Anatomy & Physiology#Cementum|cementum]] or [[Tooth - Anatomy & Physiology#Dentine|dentine]] like material. Isolated strands or islands of odontogenic epithelium are always present (ie: suggesting induction of connective tissue by the epithelial cells).
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*oral bleeding
The stroma contains neoplastic fibroblasts, with varying cellularity and the overlying epitheluim is normal.
+
*dental disruption or loss
 +
*facial or mandibular deformity
 +
*excessive salivation
 +
*growth protruding from the mouth
 +
*dysphagia occurs rarely
  
 +
===Diagnostic Imaging===
 +
Radiographs are required to differentiate this benign neoplasm from malignant or locally aggressive lesions. Skull radiographs will evaluate the oral lesion itself and thoracic radiography to evaluate for metastasies (if a malignancy is a diagnostic possibility). Radiographs typically show a soft tissue opacity in the the [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|gingiva]] region with varying degrees of mineralization. Bone involvement is '''not''' a feature of this neoplasm.
 +
Radiography cannot be used to differentiate a peripheral odontogenic fibroma from a [[Gingival Hyperplasia|hyperplastic gingival lesion]].
 +
===Biopsy===
 +
An incisional biopsy is required to obtain a definitive diagnosis
 
==Treatment==
 
==Treatment==
A surgical excision of the neoplasm should be performed. The depth of the excision is determined by the location of the origin of the neoplasm at the periodontal ligament.
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An excision of the neoplasm should be performed. The depth of the excision is determined by the location of the origin of the neoplasm at the [[Periodontal ligament - Anatomy & Physiology|periodontal ligament]].
Excision may be at the gingival level or a deep resection involving the extraction of the affected tooth and curettage of the alveolar socket.
+
Excision may be at the gingival level or a deep resection involving the extraction of the affected tooth and curettage of the alveolar socket.  
 
 
They do not recur if adequately excised.
 
 
 
 
==Prognosis==
 
==Prognosis==
 
Good following surgical resection. Recurrence is common following incomplete surgical resection.
 
Good following surgical resection. Recurrence is common following incomplete surgical resection.
 +
==References==
  
{{Learning
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*Tutt, C., Deeprose, J. and Crossley, D. (2007) '''BSAVA Manual of Canine and Feline Dentistry (3rd Edition)''' ''BSAVA''
|literature search = [http://www.cabdirect.org/search.html?q=title%3A%28%22Peripheral+Odontogenic+Fibroma%22%29+OR+%28title%3A%28epulis%29+AND+%28title%3A%28fibromatous%29+OR+title%3A%28ossifying%29%29%29 Peripheral Odontogenic Fibroma publications]
 
|Vetstream = [https://www.vetstream.com/felis/Content/Disease/dis60094.asp Odontoclastic tooth resorption]
 
}}
 
 
 
==References==
 
  
Tutt, C., Deeprose, J. and Crossley, D. (2007) '''BSAVA Manual of Canine and Feline Dentistry (3rd Edition)''' ''BSAVA''
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*Merck & Co (2008) '''The Merck Veterinary Manual'''
  
Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''' ''Merial''
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==From Pathology==
  
Verstraete, F.J.M., Ligthelmf, A.J. and Weber, A,(1992) '''The Histological Nature of Epulides in Dogs'''. Journal of comparative Pathology. (106) 169-182. 
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[[Image:epulis.gif|right|thumb|125px|<small><center>Canine Epulis (Courtesy of Alun Williams (RVC))</center></small>]]
 +
*aka: Fibromatous epulis of periodontal ligament origin
 +
Neoplastic
  
 +
*17% of cases.
 +
*Proliferation of fibrous tissue with variety of osteoid, [[Cementum - Anatomy & Physiology|cementum]] or [[Dentine - Anatomy & Physiology|dentine]]-like material.
 +
*Isolated strands or islands of odontogenic epithelium always present (ie: suggesting induction of connective tissue by the epithelial cells).
 +
*The stroma contains neoplastic fibroblasts, with varying cellularity.
 +
*The overlying epitheluim is normal.
 +
<small>
 
With thanks to Andrew Jefferies (Cambridge) and Alun Williams (RVC) for providing access to their lecture materials
 
With thanks to Andrew Jefferies (Cambridge) and Alun Williams (RVC) for providing access to their lecture materials
  
 
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J Comp. Path. 1992 (106),  169-182  The  Histological  Nature  of  Epulides  in  Dogs  F.  J.  M.  Verstraete*,  A.  J.  Ligthelmf  and  A.  WeberT. ... review of 154 oral 'epulis' from dogs reviewed with the current (at the time) human literature.
{{review}}
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</small>[[Category:Teeth_-_Proliferative_Pathology]]
 
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[[Category:To_Do_-_Clinical]]
{{OpenPages}}
 
 
 
[[Category:Teeth_-_Proliferative_Pathology]]
 
[[Category:Neoplasia]]
 
[[Category:Expert_Review - Small Animal]]
 
[[Category:Oral Diseases - Dog]]
 
[[Category:Oral Diseases - Cat]]
 
[[Category:Bones - Pathology]]
 
[[Category:Oral Proliferations]]
 
[[Category:LisaM reviewing]]
 

Revision as of 10:51, 28 June 2010



Category:WikiClinical CanineCow
Category:WikiClinical FelineCow

Epulis

Typical Signalment

  • Most common benign tumour found in the oral cavity in dogs
  • Less common in cats
  • Seen in dogs of any age but more common in those > 6years old

Description

Peripheral odontogenic fibroma is a benign tumour that arises from the periodontal ligament. It was previously known as a fibromatous epulis and ossifying epulis depending on the degree of mineralization. They present as firm, smooth swellings of the gingiva and are normally indistinguishable from gingival hyperplasia.

Diagnosis

Clinical Signs

  • halitosis
  • oral bleeding
  • dental disruption or loss
  • facial or mandibular deformity
  • excessive salivation
  • growth protruding from the mouth
  • dysphagia occurs rarely

Diagnostic Imaging

Radiographs are required to differentiate this benign neoplasm from malignant or locally aggressive lesions. Skull radiographs will evaluate the oral lesion itself and thoracic radiography to evaluate for metastasies (if a malignancy is a diagnostic possibility). Radiographs typically show a soft tissue opacity in the the gingiva region with varying degrees of mineralization. Bone involvement is not a feature of this neoplasm. Radiography cannot be used to differentiate a peripheral odontogenic fibroma from a hyperplastic gingival lesion.

Biopsy

An incisional biopsy is required to obtain a definitive diagnosis

Treatment

An excision of the neoplasm should be performed. The depth of the excision is determined by the location of the origin of the neoplasm at the periodontal ligament. Excision may be at the gingival level or a deep resection involving the extraction of the affected tooth and curettage of the alveolar socket.

Prognosis

Good following surgical resection. Recurrence is common following incomplete surgical resection.

References

  • Tutt, C., Deeprose, J. and Crossley, D. (2007) BSAVA Manual of Canine and Feline Dentistry (3rd Edition) BSAVA
  • Merck & Co (2008) The Merck Veterinary Manual

From Pathology

Canine Epulis (Courtesy of Alun Williams (RVC))
  • aka: Fibromatous epulis of periodontal ligament origin

Neoplastic

  • 17% of cases.
  • Proliferation of fibrous tissue with variety of osteoid, cementum or dentine-like material.
  • Isolated strands or islands of odontogenic epithelium always present (ie: suggesting induction of connective tissue by the epithelial cells).
  • The stroma contains neoplastic fibroblasts, with varying cellularity.
  • The overlying epitheluim is normal.

With thanks to Andrew Jefferies (Cambridge) and Alun Williams (RVC) for providing access to their lecture materials

J Comp. Path. 1992 (106), 169-182 The Histological Nature of Epulides in Dogs F. J. M. Verstraete*, A. J. Ligthelmf and A. WeberT. ... review of 154 oral 'epulis' from dogs reviewed with the current (at the time) human literature.