Difference between revisions of "Nocardia asteroides"

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*Found in soil and decaying vegetation - saprophytic
+
**Found in soil and decaying vegetation - saprophytic
*Opportunistic infection of immunocompromised animals  
+
**Opportunistic infection of immunocompromised animals  
*Infection via inhalation, wounds or teat canal; also ingestion
+
**Infection via inhalation, wounds or teat canal; also ingestion
*Causes granulomatous lesions in animals
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**Causes granulomatous lesions in animals
*Canine nocardiosis:  
+
**Canine nocardiosis:  
**Thoracic, [[Bacterial skin infections - Pathology#bacterial granulomatous dermatitis|cutaneous]] and disseminated forms
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***Thoracic, [[Bacterial skin infections - Pathology#bacterial granulomatous dermatitis|cutaneous]] and disseminated forms
**Cutaneous pyogranulomas: ulcers or granulomatous swellings with discharging fistulae  
+
***Cutaneous pyogranulomas: ulcers or granulomatous swellings with discharging fistulae  
**[[Peritonitis - Cats and Dogs|peritonitis]]
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***[[Peritonitis - Cats and Dogs|peritonitis]]
**[[Respiratory Bacterial Infections - Pathology#Nocardiosis|pleuritis]] and pyothorax with fever, anorexia and respiratory distress
+
***[[Respiratory Bacterial Infections - Pathology#Nocardiosis|pleuritis]] and pyothorax with fever, anorexia and respiratory distress
**Disseminated lesions
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***Disseminated lesions
**Treat with appropriate systemic antibiotics for 6 weeks
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***Treat with appropriate systemic antibiotics for 6 weeks
*Cattle: chronic mastitis; abortion
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**Cattle: chronic mastitis; abortion
*Pigs: abortion
+
**Pigs: abortion
*Sheep, goats, horses: wound infections; mastitis; pneumonia
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**Sheep, goats, horses: wound infections; mastitis; pneumonia
*Survives and multiplies in macrophages
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**Survives and multiplies in macrophages
*Superoxide dismutase and catalase as well as a thick peptidoglycan wall prevent activity of phagocytes  
+
**Superoxide dismutase and catalase as well as a thick peptidoglycan wall prevent activity of phagocytes  
*Chronic, progressive disease
+
**Chronic, progressive disease
*Positive modified Ziehl-Neelson
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**Positive modified Ziehl-Neelson
*Culture on blood agar and incubate under aerobic conditions at 37 degrees centigrade for 10 days
+
**Culture on blood agar and incubate under aerobic conditions at 37 degrees centigrade for 10 days
*White, powdery colonies, adherent to the agar appear after 5 days
+
**White, powdery colonies, adherent to the agar appear after 5 days
*Subculture onto Sabouraud dextrose agar yields wrinkled, orange colonies
+
**Subculture onto Sabouraud dextrose agar yields wrinkled, orange colonies
*Lesions difficult to treat due to resistance of organisms to many antimicrobials (e.g. penicillins)
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**Lesions difficult to treat due to resistance of organisms to many antimicrobials (e.g. penicillins)
*Cell-mediated immunity required
+
**Cell-mediated immunity required
 
+
[[Category:Nocardia species]][[Category:Dog]][[Category:Pig]][[Category:Cattle]]
 
+
[[Category:To_Do_-_Bacteria]]
[[Category:Nocardia species]][[Category:Dog Bacteria]][[Category:Pig Bacteria]][[Category:Cattle Bacteria]]
 
[[Category:To_Do_-_Bacteria]][[Category:To Do - Minor]]
 

Revision as of 14:15, 20 July 2010

    • Found in soil and decaying vegetation - saprophytic
    • Opportunistic infection of immunocompromised animals
    • Infection via inhalation, wounds or teat canal; also ingestion
    • Causes granulomatous lesions in animals
    • Canine nocardiosis:
      • Thoracic, cutaneous and disseminated forms
      • Cutaneous pyogranulomas: ulcers or granulomatous swellings with discharging fistulae
      • peritonitis
      • pleuritis and pyothorax with fever, anorexia and respiratory distress
      • Disseminated lesions
      • Treat with appropriate systemic antibiotics for 6 weeks
    • Cattle: chronic mastitis; abortion
    • Pigs: abortion
    • Sheep, goats, horses: wound infections; mastitis; pneumonia
    • Survives and multiplies in macrophages
    • Superoxide dismutase and catalase as well as a thick peptidoglycan wall prevent activity of phagocytes
    • Chronic, progressive disease
    • Positive modified Ziehl-Neelson
    • Culture on blood agar and incubate under aerobic conditions at 37 degrees centigrade for 10 days
    • White, powdery colonies, adherent to the agar appear after 5 days
    • Subculture onto Sabouraud dextrose agar yields wrinkled, orange colonies
    • Lesions difficult to treat due to resistance of organisms to many antimicrobials (e.g. penicillins)
    • Cell-mediated immunity required