Difference between revisions of "Brucellosis - Cattle"
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| + | **Caused by ''[[Brucella abortus]]'' | ||
| + | **Eradicated in many countries including UK | ||
| + | **Infection usually by ingestions but also venereal, skin abrasions, inhalation, transplacental | ||
| + | **Abortion storms in susceptible herds | ||
| + | **Abortion after fifth month of gestation due to placentitis | ||
| + | **Brucellae excreted in foetal fluids for 2-4 weeks following abortion and at subsequent parturitions without abortion | ||
| + | **Infection of mammary glands and lymph nodes persists for years | ||
| + | **Excreted intermittently in milk for years | ||
| + | **Seminal vesicles, ampullae, testicles and epididymus infected in bulls; necrotising orchitis | ||
| + | **Decreased fertility in cows and bulls; decreased milk production | ||
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| + | Vaccination of heifers against ''B. abortus'' in endemic regions by Strain S19, a live attenuated vaccine, stimulating a cell-mediated immune response. The vaccination of young animals interferes with serological testing. The 45/20 bacterin vaccine is less effective and the newer RB51 vaccine has no LPS O-antigen therefore not detected by serological tests and gives good protection. | ||
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| + | [[Category:To_Do_-_Clinical]] | ||
Revision as of 15:14, 23 July 2010
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This article is still under construction. |
- Caused by Brucella abortus
- Eradicated in many countries including UK
- Infection usually by ingestions but also venereal, skin abrasions, inhalation, transplacental
- Abortion storms in susceptible herds
- Abortion after fifth month of gestation due to placentitis
- Brucellae excreted in foetal fluids for 2-4 weeks following abortion and at subsequent parturitions without abortion
- Infection of mammary glands and lymph nodes persists for years
- Excreted intermittently in milk for years
- Seminal vesicles, ampullae, testicles and epididymus infected in bulls; necrotising orchitis
- Decreased fertility in cows and bulls; decreased milk production
Vaccination of heifers against B. abortus in endemic regions by Strain S19, a live attenuated vaccine, stimulating a cell-mediated immune response. The vaccination of young animals interferes with serological testing. The 45/20 bacterin vaccine is less effective and the newer RB51 vaccine has no LPS O-antigen therefore not detected by serological tests and gives good protection.