Difference between revisions of "Equine Infectious Anemia"
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*2 clear Coggins tests of all horses before movement allowed | *2 clear Coggins tests of all horses before movement allowed | ||
*Vector control: stabling, etc. | *Vector control: stabling, etc. | ||
| − | [[Category:Lentiviruses]][[Category:Horse]] | + | [[Category:Lentiviruses]][[Category:Horse Viruses]] |
[[Category:To_Do_-_Viruses]] | [[Category:To_Do_-_Viruses]] | ||
| + | [[Category:Cardiovascular_Disorders_-_Horse]] | ||
Revision as of 11:43, 29 July 2010
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This article is still under construction. |
EIA
Pathogenesis
- Virus coats red blood cells and thrombocytes
- Type III Immune complex disease develops
- Non-neutralizing antibody and complement lyse RBC's, causing:
- Jaundice
- Vasculitis
- Hemorrhage
- Diarrhoea
- Loss of condition
- Oedema
- High mortality
Epidemiology
- Notifiable in UK but endemic in parts of the US
- Animals can be carriers for years despite being antibody-positive
- Transfer is mechanical via vectors:
- Mosquitoes transfer infected macrophages
- Also transferred via infected needles, semen and milk
- Infected horses have lifetime latent infection of macrophages with recurring bouts of virus when immunocompromised
Diagnosis
- Coggins test required for horse movement in the US:
- Serum antibody by immunodiffusion in infected horse spleen
Control
- Slaughter of infected animal
- 2 clear Coggins tests of all horses before movement allowed
- Vector control: stabling, etc.