Difference between revisions of "Colitis, Granulomatous"

From WikiVet English
Jump to navigation Jump to search
m (Text replace - "Category:Large Intestinal_Disorders_-_Horse" to "Category:Large Intestinal Diseases - Horse")
Line 20: Line 20:
 
[[Category:Enteritis,_Proliferative]]
 
[[Category:Enteritis,_Proliferative]]
 
[[Category:To_Do_-_Clinical]]
 
[[Category:To_Do_-_Clinical]]
[[Category:Large Intestinal Diseases - Horse]]
+
[[Category:Large Intestinal_Disorders_-_Horse]]

Revision as of 13:29, 30 July 2010

  • Affects the horse.
    • Usually young to middle age adults.
  • Unknown cause.
  • Is a one-off occurence rather than a herd problem.
  • As in Johnes Diseaase, there is chronic ongoing diarrhoea with eventual death.
  • Thickening of mucosa is seen mainly in the caecum and colon.
    • Lamina propria contains granulomatous inflammatory tissue (as in Johne's Disease).
    • Sometimes large numbers of eosinophils are seen.
  • Mesenteric lymph nodes are very large.
  • At laparotomy lymph node appears like lymphosarcoma (very large).
  • Cannot do much to remedy the condition once it has started.
    • Progresses to death.

Proposed Pathogenesis

  • Hypersensitivity reaction to trichoneme parasite?
    • Possibly an idiosyncratic response to the encysted larvae.
  • Dysbacteriosis or disordered immune response?