Difference between revisions of "Stephanofilariasis"

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*Caused by [[Stephanofilaria stilesi|''Stephanofilaria stilesi'']]
 
*Caused by [[Stephanofilaria stilesi|''Stephanofilaria stilesi'']]
 
*Occurs in cattle, buffalo, goats
 
*Occurs in cattle, buffalo, goats
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**[[Skin Glossary - Pathology|Epidermal hyperkeratosis, parakeratosis, acanthosis]], eosinophilic microabscesses and crusts
 
**[[Skin Glossary - Pathology|Epidermal hyperkeratosis, parakeratosis, acanthosis]], eosinophilic microabscesses and crusts
  
===Gross pathology===
 
*Lesions begin as small circular patches on the ventral midline with serous exudate. 
 
*These enlarge and coalesce producing lesions 25cm or more in diameter. 
 
*Hemorrhage develops along the periphery while the older, central areas develop scabs or dry crusts. 
 
*Healing lesions are alopecic, lichenified plaques.
 
*Lesions may also occur on the flank, udder, teats, face and neck.
 
  
 
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[[Category:To_Do_-_Clinical]]
 
 
===Histopathology===
 
*Adult parasites occur within cystic diverticula of hair follicles or free within the adjacent dermis. 
 
**Parasites may have lateral cords and lateral cuticular projections. 
 
**The thick intestine is distinctive.
 
**Microfilariae within uteri is the key feature. 
 
***Microfilariae also occur free within the dermis, in dermal lymphatics, or in the surface exudate. 
 
*There is little dermal reaction to adults in cystic hair follicles, but their presence within the dermis elicits eosinophilic and mononuclear inflammation.
 
 
 
===Differential diagnosis===
 
# Pelodera strongyloides: 
 
#*Rhabditid parasite, adults 1-1.5mm long, found in follicles
 
#*uteri contain eggs, not microfilaria.
 
# Dermatophytosis (Trichophyton verrucosum is most common)
 
# Mange (Chorioptes bovis)
 
# Fly bite dermatitis
 
# Contact dermatitis
 
# Zn-responsive dermatitis
 
# Other subcutaneous filarid parasites: 
 
#*Parafilaria bovicola (adult worms 30-70mm long, found coiled in nodules in subcutaneous and intramuscular connective tissues; not seen in US)
 
#*Onchocerca gutterosa (adult worms 60mm long, found in nuchal ligament and subcutaneous connective tissues).
 
 
 
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[[Category:Integumentary System - Helminth Infections]]
 
[[Category:To_Do_-_Dermatology]][[Category:To Do - Minor]]
 

Revision as of 06:09, 4 August 2010




  • Caused by Stephanofilaria stilesi
  • Occurs in cattle, buffalo, goats
  • Transmitted by flies
  • Affects ventral midline (other species affect different areas of body)
  • Grossly:
    • Foci extending to large areas
    • Errect hairs, epidermal haemorrhage, serum exudate -> crusts
  • Microscopically: