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Category:Cell Mediated Autoimmune Diseases (view source)

Revision as of 15:01, 11 August 2010

664 bytes removed ,  15:01, 11 August 2010
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===1. [[Rheumatoid Arthritis]]===
 
===1. [[Rheumatoid Arthritis]]===
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===2. Diabetes Mellitus type I===
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===2.  
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[[Image:Diabetes Mellitus Type IV hypersensitivity.jpg|right|thumb|150px|Diabetes Mellitus-Brian Catchpole RVC 2008]]
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'''Pathogenesis:'''
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* [[Type IV Hypersensitivity - WikiBlood|Type IV hypersensitivity]]
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* The CTLs think that all the beta cells in the pancreas are infected by a virus, as it wrongly detects a self antigen presented by the MHC class I on the surface of the cell as foreign.
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* Autoreactive CD8+ CTLs are inadvertently activated, destroying the beta cells, thus preventing the secretion of insulin and causing diabetes type 1 (see diagram).
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[[Category:Cell Mediated Autoimmune Diseases]][[Category:To Do - Blood]]
   
===3. Hypothyroidism (lymphocytic throiditis)===
 
===3. Hypothyroidism (lymphocytic throiditis)===
  
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