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Category:Cell Mediated Autoimmune Diseases (view source)
Revision as of 15:00, 11 August 2010
, 15:00, 11 August 2010Created page with " ===1. Rheumatoid Arthritis=== ===2. Diabetes Mellitus type I=== [[Image:Diabetes Mellitus Type IV hypersensitivity.jpg|right|thumb|150px|Diabetes Mellitus-Brian Catchpole ..."
===1. [[Rheumatoid Arthritis]]===
===2. Diabetes Mellitus type I===
[[Image:Diabetes Mellitus Type IV hypersensitivity.jpg|right|thumb|150px|Diabetes Mellitus-Brian Catchpole RVC 2008]]
'''Pathogenesis:'''
* [[Type IV Hypersensitivity - WikiBlood|Type IV hypersensitivity]]
* The CTLs think that all the beta cells in the pancreas are infected by a virus, as it wrongly detects a self antigen presented by the MHC class I on the surface of the cell as foreign.
* Autoreactive CD8+ CTLs are inadvertently activated, destroying the beta cells, thus preventing the secretion of insulin and causing diabetes type 1 (see diagram).
[[Category:Cell Mediated Autoimmune Diseases]][[Category:To Do - Blood]]
===3. Hypothyroidism (lymphocytic throiditis)===
'''Pathogenesis:''' [[Type IV Hypersensitivity - WikiBlood|Type IV hypersensitivity]]
* T cell mediated
[[Category:Cell Mediated Autoimmune Diseases]][[Category:To Do - Blood]]
===4. Hypoadrenocorticism (Addisons disease)===
'''Pathogenesis:''' [[Type IV Hypersensitivity - WikiBlood|Type IV hypersensitivity]]
[[Category:Cell Mediated Autoimmune Diseases]][[Category:To Do - Blood]]
[[Category:Autoimmune Diseases]]