Difference between revisions of "Category:Primary Immunodeficiency"

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===Laboratory Examples of Severe Combined Deficiency===
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=== [[Severe Combined Deficiency - Laboratory Examples]]===
[[Image:Nude Mouse.jpg|right|thumb|150px|Athymic Nude Mouse - Armin Kübelbeck 2008]]
 
*Severe Combined Immune Deficiency(SCID)
 
**No functional [[Lymphocytes#B cells|B cells]] or [[Lymphocytes#T cells|T cells]]
 
 
 
*Athymic nude mice (no [[Thymus - Anatomy & Physiology|thymus]])
 
**No functional [[Lymphocytes#T cells|T cells]]
 
**Cell-mediated immunodeficiency
 
 
 
*Knock-out mice
 
**E.g. Gene coding for  CD4, CD8, IL-10 removed
 
  
 
[[Category:Immunodeficiencies]]
 
[[Category:Immunodeficiencies]]

Revision as of 14:02, 12 August 2010

  • Primary immunodeficiencies may affect either the innate immune system or the adaptive immune system
  • They are categorised by either the type or the developmental stage of the cells involved
  • Lymphoid cell disorders affect T cells or B cells (or both)
  • Myeloid cell disorders affect phagocytic function
  • The severity of the immunodeficiency depends on at which stage in development the problem occurs
    • E.g. Defects early on in development will affect the entire immune system
  • T cell deficiencies can affect both the cell-mediated and humoral response as T cells play a central role in the immune system

Primary Innate Immunity Deficiencies Primary Adaptive Immunity Deficiencies


Severe Combined Deficiency - Laboratory Examples

Subcategories

This category has the following 2 subcategories, out of 2 total.

Pages in category "Primary Immunodeficiency"

This category contains only the following page.