Difference between revisions of "Blood Groups - Dog"
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| + | | See also: | ||
| + | |'''[[Transfusion Medicine - Introduction|Transfusion Medicine - Introduction]]<br>[[Blood Collection for Transfusion|Blood Collection for Transfusion]]<br>[[Blood Groups - Cat|Blood Groups - Cat ]]''' | ||
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==Introduction== | ==Introduction== | ||
| − | The most widely used blood grouping system is the | + | The most widely used blood grouping system is the Dog Erythrocyte Antigen system (DEA) and within this system eight blood groups exist. |
DEA 1 (DEA 1.1 DEA 1.2), DEA2 - DEA 7. | DEA 1 (DEA 1.1 DEA 1.2), DEA2 - DEA 7. | ||
| − | Often Rottweilers, Labradors and Golden | + | Often Rottweilers, Labradors and Golden retrivers have DEA 1.1 or DEA 1.2 positive blood types and Greyhounds and German Shepherd Dogs are frequently DEA 1.1 and DEA 1.2 negative. For this reason greyhounds are commonly used as donors. |
==Alloantibodies== | ==Alloantibodies== | ||
Unlike [[Blood Groups - Cat|cats]] dogs do not have natural alloantibodies against other blood groups. | Unlike [[Blood Groups - Cat|cats]] dogs do not have natural alloantibodies against other blood groups. | ||
| − | There is no major risk for the first transfusion | + | There is no major risk for the first transfusion unlike the cat, compatibility tests are not required for the dogs first blood transfusion. |
| − | Alloantibodies form within 5-7 days of the first transfusion and consequently if a second | + | Alloantibodies form within 5-7 days of the first transfusion and consequently if a second tranfusion is required 5 days later than the original transfusion compatibility tests are necessary. |
Blood typing can be carried out using commercial in house kits or can be sent away to a reference laboratory. | Blood typing can be carried out using commercial in house kits or can be sent away to a reference laboratory. | ||
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Dogs can be positve for one of DEA 1.1 or DEA 1.2 or negative for both DEA 1.1 and 1.2. | Dogs can be positve for one of DEA 1.1 or DEA 1.2 or negative for both DEA 1.1 and 1.2. | ||
DEA 1.1 and DEA 1.2 are the most antigenic and hence ideally a donor would be DEA 1.1 and DEA 1.2 negative. | DEA 1.1 and DEA 1.2 are the most antigenic and hence ideally a donor would be DEA 1.1 and DEA 1.2 negative. | ||
| − | Transfusion reactions can occur when DEA 1.1 and 1.2 negative dogs | + | Transfusion reactions can occur when DEA 1.1 and 1.2 negative dogs recieve DEA 1.1 or 1.2 positive blood. |
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| − | + | [[Neonatal Isoerythrolysis|Neonatal isoerythrolysis]] can also occur in dogs. This happens when a DEA 1.1 negative female which has previosuly been sensitised to DEA 1.1 positive blood is mated to a DEA 1.1 positive male. | |
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==References== | ==References== | ||
Transfusion Therapy. Lymphoreticular and Haematology module. 4th year notes. Royal Veterinary College London. 2009. | Transfusion Therapy. Lymphoreticular and Haematology module. 4th year notes. Royal Veterinary College London. 2009. | ||
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[[Category:Transfusion Medicine]] | [[Category:Transfusion Medicine]] | ||
| − | [[Category:Dog | + | [[Category:Dog]] |
Revision as of 21:49, 15 August 2010
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This article is still under construction. |
| See also: | Transfusion Medicine - Introduction Blood Collection for Transfusion Blood Groups - Cat |
Introduction
The most widely used blood grouping system is the Dog Erythrocyte Antigen system (DEA) and within this system eight blood groups exist. DEA 1 (DEA 1.1 DEA 1.2), DEA2 - DEA 7. Often Rottweilers, Labradors and Golden retrivers have DEA 1.1 or DEA 1.2 positive blood types and Greyhounds and German Shepherd Dogs are frequently DEA 1.1 and DEA 1.2 negative. For this reason greyhounds are commonly used as donors.
Alloantibodies
Unlike cats dogs do not have natural alloantibodies against other blood groups. There is no major risk for the first transfusion unlike the cat, compatibility tests are not required for the dogs first blood transfusion. Alloantibodies form within 5-7 days of the first transfusion and consequently if a second tranfusion is required 5 days later than the original transfusion compatibility tests are necessary.
Blood typing can be carried out using commercial in house kits or can be sent away to a reference laboratory.
Dogs can be positve for one of DEA 1.1 or DEA 1.2 or negative for both DEA 1.1 and 1.2.
DEA 1.1 and DEA 1.2 are the most antigenic and hence ideally a donor would be DEA 1.1 and DEA 1.2 negative.
Transfusion reactions can occur when DEA 1.1 and 1.2 negative dogs recieve DEA 1.1 or 1.2 positive blood.
Neonatal isoerythrolysis can also occur in dogs. This happens when a DEA 1.1 negative female which has previosuly been sensitised to DEA 1.1 positive blood is mated to a DEA 1.1 positive male.
References
Transfusion Therapy. Lymphoreticular and Haematology module. 4th year notes. Royal Veterinary College London. 2009.