Difference between revisions of "Case 1"
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*Heart has a ''globoid'' shape | *Heart has a ''globoid'' shape | ||
*Ventricular wall measurements: | *Ventricular wall measurements: | ||
| − | **Interventricular septum; 12mm[[Image:hypertrophic cardiomyopathy 2.jpg|right|thumb|125px|<small><center>'''Hypertrophic cardiomyopathy (cat)'''. Courtesy of T. Scase</center></small>]] | + | **Interventricular septum; 12mm |
| + | [[Image:hypertrophic cardiomyopathy 2.jpg|right|thumb|125px|<small><center>'''Hypertrophic cardiomyopathy (cat)'''. Courtesy of T. Scase</center></small>]] | ||
**Right ventricular wall; 3mm | **Right ventricular wall; 3mm | ||
**Left ventricular wall; 10mm | **Left ventricular wall; 10mm | ||
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The other body systems were examined.<br> | The other body systems were examined.<br> | ||
No further abnormalities were found. | No further abnormalities were found. | ||
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==Histopathology== | ==Histopathology== | ||
| − | [[Image:Case pic 3.jpg| | + | [[Image:Case pic 3.jpg|left|thumb|125px|<small><center>'''Histology; hypertrophic cardiomyopathy'''. Courtesy of K. Hughes</center></small>]] |
Samples were taken for histological examination (Stained with H and E): | Samples were taken for histological examination (Stained with H and E): | ||
*The cardiac myocytes are multifocally widely spaced and infiltrated by streams of spindle shaped cells (fibroblasts). | *The cardiac myocytes are multifocally widely spaced and infiltrated by streams of spindle shaped cells (fibroblasts). | ||
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Some sections were stained with Massons Trichrome: | Some sections were stained with Massons Trichrome: | ||
| + | [[Image:Case pic 4.jpg|right|thumb|125px|<small><center>'''Histology; Massons Trichrome'''. Courtesy of K. Hughes</center></small>]] | ||
| − | * This confirmed the presence of large, multifocal areas of fibrosis within the inner third of the myocardium and extending to the endocardial surface. | + | *This confirmed the presence of large, multifocal areas of fibrosis within the inner third of the myocardium and extending to the endocardial surface. |
| − | * Multifocally the fibrosis surrounds individual atrophied myocytes. | + | *Multifocally the fibrosis surrounds individual atrophied myocytes. |
| − | * There is mural thickening (smooth muscle hypertrophy) of the intramyocardial arteries. | + | *There is mural thickening (smooth muscle hypertrophy) of the intramyocardial arteries. |
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Revision as of 12:06, 31 August 2007
Signalment
- 7 year old
- Male neutered
- Domestic short haired cat
History
- Fully vaccinated
- Sudden death at home
- No other clinical abnormalities
Imaging
Haematology/Biochemistry
Gross Pathology
The following data and pictures were taken at post-mortem examination:
Cardiovascular system:
- Heart has a globoid shape
- Ventricular wall measurements:
- Interventricular septum; 12mm
- Right ventricular wall; 3mm
- Left ventricular wall; 10mm
- Pericardium is fatty, shiny and intact
No embolic thrombi were found in the abdominal aorta.
The other body systems were examined.
No further abnormalities were found.
Histopathology
Samples were taken for histological examination (Stained with H and E):
- The cardiac myocytes are multifocally widely spaced and infiltrated by streams of spindle shaped cells (fibroblasts).
Some sections were stained with Massons Trichrome:
- This confirmed the presence of large, multifocal areas of fibrosis within the inner third of the myocardium and extending to the endocardial surface.
- Multifocally the fibrosis surrounds individual atrophied myocytes.
- There is mural thickening (smooth muscle hypertrophy) of the intramyocardial arteries.