Difference between revisions of "Neosporosis - Cattle"

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==Introduction==
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{{unfinished}}
Caused by the protozoan parasite ''[[Neospora|Neospora caninum]]'' and is the commonest cause of abortion in dairy cattle. ''Neospora caninum'' is similar to ''[[Toxoplasma gondii]]'' and although the complete life cycle of the protozoa is unknown, the dog has been found to be the definitive host.
 
  
Stillborn calves can be born from infected dams and congenitally infected calves may be  born with encephalomyelitis. Abortion usually occurs between 5-7 months of gestation but can occur as early as 3 months.
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==Description==
Most cases of infection occur via vertical transmission however animals can become infected from their mothers milk, by eating food and water contaminated with dog faeces containing '''Neospora caninum'' oocysts, or from cow to cow.
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Caused by the protozoan parasite [[Neospora|Neospora caninum]] and is the commonest cause of abortion dairy cattle.Neospora caninum is similar to toxoplasma gondii and although the complte lifecycle of the protozoa is unknown, the dog has been found to be the definitive host.
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Stillborn calves can be born from infected dams and congenitally infected calves may be  born with encephalomyelitis. Abortion usually occurs between 5-7 months of gestation but can occur as early as 3 months. Often no other clinical signs are present in the cow.
  
 
==Signalment==
 
==Signalment==
Neospora has been documented to infect cattle, both beef and dairy, sheep, goats and dogs.
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Neospora has been documented to infect cattle, sheep goats and the dog.
There is no age predilection.
 
 
 
 
==Diagnosis==
 
==Diagnosis==
The histological appearance of lesions on an aborted fetus can be enough to confirm a diagnosis.
 
Additionally antibodies to the protozoa can be identified via serological methods.
 
 
 
==Clinical Signs==
 
==Clinical Signs==
Often infected cattle present with no clinical signs other than abortion.  
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Often infected cattle present with no clinical signs other than abortion. Calves can be born with encephalomyelitis causing various neurological signs such as paresis. Repeat abortions are often reported in affected animals due to a persistent infection.
 
 
Calves can be born with encephalomyelitis causing various neurological signs such as paresis, decreased reflexes and ataxia.  
 
 
 
Repeat abortions are often reported in affected animals due to a persistent infection.
 
  
 
==Laboratory Tests==
 
==Laboratory Tests==
An indirect fluorescent antibody test can be used to detect antibodies from samples and an [[ELISA testing|ELISA]] is available which will also detect antibodies.
 
A PCR method to identify antigen is currently under development
 
 
 
==Pathology==
 
==Pathology==
Non-suppurative encephalitis is most commonly seen in aborted foetuses. Additionally non suppurative [[Myocarditis|myocarditis]], myositis and widespread non suppurative infiltrates in other organs are often found. Tissue cysts will be present and can be identified.
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Non-suppurative encephalitis is most commonly seen in aborted faeces.
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non suppurative myocarditis
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myositis
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widespread non suppurative infiltrates in other organs
  
Hepatitis may also be found in epidemic abortions.
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==Treatment==
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Do not allow dogs access to calving cows, placental membranes and aborted or dead calves
  
Signs of placentitis will be evident on inspection of the placenta.
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Do not allow dogs to defecate in cattle feeding areas
  
==Control==
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Identify and cull seropositive cattle, or do not breed from them or their progeny
To avoid the transmission of ''Neospora caninum'' oocysts from dogs to cattle, dogs should not be allowed access to calving cows, placental membranes and aborted or dead calves. Dogs should also be stopped from defecating in cattle feeding areas.
 
  
Seropositive cattle should be identified and culled and none of their progeny should be bred from and hence seronegative cattle should be selected for breeding.
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Select seronegative cattle for breeding
  
[[Vaccines|Vaccination]] is possible but only in the USA.
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Vaccinate is possible but only in the USA.
 
It is a killed protozoal vaccine for healthy, pregnant cows and is given in the first 3 weeks of pregnancy and then every 3-4 weeks during gestation.
 
It is a killed protozoal vaccine for healthy, pregnant cows and is given in the first 3 weeks of pregnancy and then every 3-4 weeks during gestation.
 
Revaccination with 2 doses should be undertaken during each subsequent pregnancy.
 
Revaccination with 2 doses should be undertaken during each subsequent pregnancy.
  
==Literature Search==
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==Prognosis==
[[File:CABI logo.jpg|left|90px]]
 
 
 
 
 
Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
 
<br><br><br>
 
[http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=neospor*&occuring1=title&rowId=2&options2=AND&q2=cattle&occuring2=od&rowId=3&options3=AND&q3=&occuring3=freetext&x=59&y=11&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all Neosporosis in cattle publications]
 
 
 
  
{{review}}
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[[Category:Cattle]]
[[Category:Reproductive Diseases - Cattle]][[Category:Reproductive Diseases - Sheep]][[Category:Reproductive Diseases - Goat]]
 
[[Category:Neurological Diseases - Cattle]][[Category:Neurological Diseases - Sheep]][[Category:Neurological Diseases - Goat]]
 
 
[[Category:Tissue_Cyst_Forming_Coccidia]]
 
[[Category:Tissue_Cyst_Forming_Coccidia]]
[[Category:Brian Aldridge reviewing]]
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[[Category:To_Do_-_Caz]]

Revision as of 11:51, 19 August 2010



Description

Caused by the protozoan parasite Neospora caninum and is the commonest cause of abortion dairy cattle.Neospora caninum is similar to toxoplasma gondii and although the complte lifecycle of the protozoa is unknown, the dog has been found to be the definitive host.

Stillborn calves can be born from infected dams and congenitally infected calves may be born with encephalomyelitis. Abortion usually occurs between 5-7 months of gestation but can occur as early as 3 months. Often no other clinical signs are present in the cow.

Signalment

Neospora has been documented to infect cattle, sheep goats and the dog.

Diagnosis

Clinical Signs

Often infected cattle present with no clinical signs other than abortion. Calves can be born with encephalomyelitis causing various neurological signs such as paresis. Repeat abortions are often reported in affected animals due to a persistent infection.

Laboratory Tests

Pathology

Non-suppurative encephalitis is most commonly seen in aborted faeces. non suppurative myocarditis myositis widespread non suppurative infiltrates in other organs

Treatment

Do not allow dogs access to calving cows, placental membranes and aborted or dead calves

Do not allow dogs to defecate in cattle feeding areas

Identify and cull seropositive cattle, or do not breed from them or their progeny

Select seronegative cattle for breeding

Vaccinate is possible but only in the USA. It is a killed protozoal vaccine for healthy, pregnant cows and is given in the first 3 weeks of pregnancy and then every 3-4 weeks during gestation. Revaccination with 2 doses should be undertaken during each subsequent pregnancy.

Prognosis