Difference between revisions of "Pneumocystis carinii"
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*Important cause of pneumonia in humans associated with immunodeficiency states | *Important cause of pneumonia in humans associated with immunodeficiency states | ||
| − | *It has been occasionally reported in young or immunosuppressed animals (e.g. Arabian foals with congenital immunodeficiency) | + | *It has been occasionally reported in young or immunosuppressed animals (e.g. Arabian foals with [[Equine Severe Combined Immune Deficiency|congenital immunodeficiency]]) |
*Grossly: | *Grossly: | ||
**Diffuse [[Lungs Inflammatory - Pathology#Interstitial pneumonia|interstitial]] [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]] | **Diffuse [[Lungs Inflammatory - Pathology#Interstitial pneumonia|interstitial]] [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]] | ||
Revision as of 21:44, 7 October 2010
- Important cause of pneumonia in humans associated with immunodeficiency states
- It has been occasionally reported in young or immunosuppressed animals (e.g. Arabian foals with congenital immunodeficiency)
- Grossly:
- Diffuse interstitial pneumonia
- Patches of firmness or consolidation
- Histologically:
- Alveoli are filled with pale staining acidophilic material (= trophozoite and cyst forms of the organism)
- It is thought that as P. carinii is often present as a latent infection, alveolar macrophages normally control the organism - a process which fails in immunodeficient states