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Renin Angiotensin Aldosterone System (view source)
Revision as of 09:39, 26 October 2010
, 09:39, 26 October 2010no edit summary
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[[Image:RAS.jpg|right|thumb|250px|<small><center> Schematic of the RAAS ©RVC 2008</center></small>]]
[[Image:RAS.jpg|right|thumb|250px|<small><center> Schematic of the RAAS ©RVC 2008</center></small>]]
+==Introduction==
* Allows an animal’s salt intake to vary without any great affect on ECF volume or arterial pressure
* Allows an animal’s salt intake to vary without any great affect on ECF volume or arterial pressure
* If an animal’s salts intake increased 50x its blood pressure would only increase 5-6mmHg
* If an animal’s salts intake increased 50x its blood pressure would only increase 5-6mmHg
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=====Advantages of Constriction of the Efferent Arteriole=====
=====Advantages of Constriction of the Efferent Arteriole=====
−* If you increase the resistance in the kidneys you contribute to increasing total peripheral resistance. This helps to return blood pressure towards normal. (Angiotensin 2 also has vasoconstrictive effects in other organs.)
* If you increase the resistance in the kidneys you contribute to increasing total peripheral resistance. This helps to return blood pressure towards normal. (Angiotensin 2 also has vasoconstrictive effects in other organs.)
* The kidneys can tolerate the reduced perfusion allowing blood to be prioritised to organs which need it like the brain and heart.
* The kidneys can tolerate the reduced perfusion allowing blood to be prioritised to organs which need it like the brain and heart.
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====Effects of Angiotensin 2 On Sodium====
====Effects of Angiotensin 2 On Sodium====
−* Induces insertion of Na<sup>+</sup> channels into renal tubules via stimulation of AT<sub>1</sub> receptors
* Induces insertion of Na<sup>+</sup> channels into renal tubules via stimulation of AT<sub>1</sub> receptors
* Proximal tubule:
* Proximal tubule:
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==Revision==
==Revision==
−Use the [[Important Hormonal Regulators of the Kidney - Renal Flash Cards - Anatomy & Physiology|flash card revision resource]] for this section to test yourself.
Use the [[Important Hormonal Regulators of the Kidney - Renal Flash Cards - Anatomy & Physiology|flash card revision resource]] for this section to test yourself.