Difference between revisions of "Permethrin Toxicity"
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==Introduction== | ==Introduction== | ||
| − | Permethrin is the active ingredient of many 'spot-on' | + | Permethrin is the active ingredient of many 'spot-on' paraciticides used in the control of fleas and ticks in dogs <ref> '''Clinical effects and outcome of feline permethrin spot-on poisonings reported to the Veterinary Poisons information Service (VPIS), London''', ''Journal of Feline Medicine and Surgery''(2007)'''9''',335-339 accessed on http://www.fabcats.org/esfm/permethrin.pdf 07.11.2010 </ref>. |
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==Signalment== | ==Signalment== | ||
Permethrin poisoning in most commonly seen in cats who have inadvertently been administered spot-on products intended for use in dogs, or who have had contact with dogs following application of the preparations <ref name="multiples"> '''BSAVA Manual of Canine and Feline Emergency and Critical Care''', Chapter 19, Second Edition, 2007 </ref>. | Permethrin poisoning in most commonly seen in cats who have inadvertently been administered spot-on products intended for use in dogs, or who have had contact with dogs following application of the preparations <ref name="multiples"> '''BSAVA Manual of Canine and Feline Emergency and Critical Care''', Chapter 19, Second Edition, 2007 </ref>. | ||
==Diagnosis== | ==Diagnosis== | ||
===Clinical Signs=== | ===Clinical Signs=== | ||
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===Laboratory Tests=== | ===Laboratory Tests=== | ||
===Pathology=== | ===Pathology=== | ||
| − | The spot-on canine preparations are often quite concentrated.<ref name="multiples"> '''BSAVA Manual of Canine and Feline Emergency and Critical Care''', Chapter 19, Second Edition, 2007 </ref>. Cats lack the enzyme glucuronidase transferase | + | The spot-on canine preparations are often quite concentrated.<ref name="multiples"> '''BSAVA Manual of Canine and Feline Emergency and Critical Care''', Chapter 19, Second Edition, 2007 </ref>. Cats lack the enzyme glucuronidase transferase and is therefore unable to utilise the metabolic pathway that dogs and other animals use to break down permethrin into glucuronides and sulphates. |
==Treatment== | ==Treatment== | ||
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==Prognosis== | ==Prognosis== | ||
==References== | ==References== | ||
<references/> | <references/> | ||
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Revision as of 20:05, 8 November 2010
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This article is still under construction. |
Introduction
Permethrin is the active ingredient of many 'spot-on' paraciticides used in the control of fleas and ticks in dogs [1].
Signalment
Permethrin poisoning in most commonly seen in cats who have inadvertently been administered spot-on products intended for use in dogs, or who have had contact with dogs following application of the preparations [2].
Diagnosis
Clinical Signs
Laboratory Tests
Pathology
The spot-on canine preparations are often quite concentrated.[2]. Cats lack the enzyme glucuronidase transferase and is therefore unable to utilise the metabolic pathway that dogs and other animals use to break down permethrin into glucuronides and sulphates.
Treatment
Prognosis
References
- ↑ Clinical effects and outcome of feline permethrin spot-on poisonings reported to the Veterinary Poisons information Service (VPIS), London, Journal of Feline Medicine and Surgery(2007)9,335-339 accessed on http://www.fabcats.org/esfm/permethrin.pdf 07.11.2010
- ↑ 2.0 2.1 BSAVA Manual of Canine and Feline Emergency and Critical Care, Chapter 19, Second Edition, 2007