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| ==Introduction== | | ==Introduction== |
| A congenital malformation or degeneration of the mitral valve leaflets and its supporting structures(chordae tendineae, papillary muscles, valvular leaflets, annulus) results in valvular regurgitation (insufficiency) | | A congenital malformation or degeneration of the mitral valve leaflets and its supporting structures(chordae tendineae, papillary muscles, valvular leaflets, annulus) results in valvular regurgitation (insufficiency) |
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| + | ''Incidence:'' |
| + | [[Image:AV valve dysplasia cat.jpg|right|thumb|200px|<small><center>'''Mitral dyplasia'''. Courtesy of A. Jefferies</center></small>]] |
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| Chronic mitral regurgitation leads to volume overload of the left heart, which results in dilatation (eccentric hypertrophy) of the left ventricle and atrium. When mitral regurgitation is severe, cardiac output decreases, which results in signs of left sided cardiac failure [[LCHF]] and pulmonary venous congestion. Dilatation of the left-sided chambers predisposes affected animals to [[arrhythmias]]. In some cases, malformation of the mitral valve complex causes a degree of valvular stenosis as well as insufficiency. | | Chronic mitral regurgitation leads to volume overload of the left heart, which results in dilatation (eccentric hypertrophy) of the left ventricle and atrium. When mitral regurgitation is severe, cardiac output decreases, which results in signs of left sided cardiac failure [[LCHF]] and pulmonary venous congestion. Dilatation of the left-sided chambers predisposes affected animals to [[arrhythmias]]. In some cases, malformation of the mitral valve complex causes a degree of valvular stenosis as well as insufficiency. |
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| ==Literature Search== | | ==Literature Search== |
| ==References== | | ==References== |
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− | ==From Pathology==
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− | Often associated with mitral regurgitation and left atrial volume overload. Usually progresses to left sided heart failure.
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− | ''Incidence:''
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− | [[Image:AV valve dysplasia cat.jpg|right|thumb|200px|<small><center>'''Mitral dyplasia'''. Courtesy of A. Jefferies</center></small>]]
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− | *Most common congenital defect in cats.
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− | *Also reported in pure breed dogs E.g GSD, Great Danes.
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− | ''Clinical Signs:''
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− | *Often murmur is the only clinical sign; pansystolic with increased intensity over the mitral valve area.
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− | *May also see exercise intolerance, dyspnoea and coughing.
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− | ''Diagnosis:''
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− | *Left atrial enlargement on radiology and ECG.
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− | *Doppler echocardiography can dtect abnormal flow.
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− | ''Treatment:''
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− | *Prognosis poor, medically manage left heart failure with ACE-inhibitors etc.
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| [[Category:Cardiovascular_System_-_Developmental_Pathology]][[Category:to_Do_Katie]] | | [[Category:Cardiovascular_System_-_Developmental_Pathology]][[Category:to_Do_Katie]] |