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39 bytes added ,  12:21, 16 November 2010
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==T Cell Tolerance==
 
==T Cell Tolerance==
During [[T cells|T cell]] development within the [[Thymus - Anatomy & Physiology|thymus]], genes encoding the T cell receptors are rearranged, resulting in adult cells that are able to recognise antigen fragments displayed by the host MHC molecule. Some receptors however will be self-reactive, i.e. they bind strongly to antigens expressed by the host's own tissues ('''autoantigens'''), inducing immune reactions that could be damaging to the host ([[Autoimmune Diseases - Introduction#Autoimmune diseases|autoimmune diseases]]); they must be deleted or suppressed.  
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During [[T cells|T cell]] development within the [[Thymus - Anatomy & Physiology|thymus]], genes encoding the T cell receptors are rearranged, resulting in adult cells that are able to recognise antigen fragments displayed by the host [[Major Histocompatability Complexes|MHC molecule]]. Some receptors however will be self-reactive, i.e. they bind strongly to antigens expressed by the host's own tissues ('''autoantigens'''), inducing immune reactions that could be damaging to the host ([[Autoimmune Diseases - Introduction#Autoimmune diseases|autoimmune diseases]]); they must be deleted or suppressed.  
    
===Central Tolerance===
 
===Central Tolerance===
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