Difference between revisions of "Phosphorus"

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==Phosphorus==
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{{OpenPagesTop}}
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==Overview==
  
Phosphorus is the third most abundent intracellular ion:  
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Phosphorus is the third most abundant intracellular ion:  
#Potassium
 
#Magnesium
 
#Phosphorus (as Phosphate)
 
  
Within the body it is found as Phosphate ions or Phosphate within bone.
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1. Potassium
The majority (~95%) is combined with Calcium in bone, forming Hydroxyapatite. Less than 1% is found in the extracelullar fluid.
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2. Magnesium
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3. Phosphorus (as Phosphate)
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Within the body it is found as Phosphate ions, or Phosphate within bone. The majority (~95%) is combined with Calcium in bone, forming Hydroxyapatite. Less than 1% is found in the extracelullar fluid.
  
 
==Homeostasis==
 
==Homeostasis==
  
Serum concentrations of phosphorus are maintained by dietary sources. It is absorbed across the intestine via ''Passive diffusion'' and ''[[Calcium#Calcitriol (Active Vitamin D3)|Vitamin D]] mediated active transport''.
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Serum concentrations of phosphorus are maintained by dietary sources. It is absorbed across the intestine via ''passive diffusion'' and ''[[Calcium#Calcitriol (Active Vitamin D3)|vitamin D]] mediated active transport''. Phosphorus is excreted in the urine or saliva (particularly in ruminants).
 
 
Phosphorus is excreted in the urine or saliva (particularly in ruminants).
 
  
 
===Hormonal Regulation===
 
===Hormonal Regulation===
  
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[[Calcium#Parathyroid Hormone (PTH)|'''PTH''']]
  
[[Calcium#Parathyroid Hormone (PTH)|'''PTH''']]
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PTH mobilises phosphorus from bone, acting to increase the plasma concentration of P. It increases phosphorus loss in the urine and saliva, so ultimately, PTH acts to remove phosphorus from the body entirely.
*Mobilises phosphorus from bone, acting to increase plasma concentration of P
 
*Increases phosphorus loss in the urine and saliva, acting to decrease plasma concentration
 
So ultimately, PTH acts to remove phosphorus from the body entirely.
 
  
 
[[Calcium#Calcitriol (Active Vitamin D3)|'''Calcitriol''']]
 
[[Calcium#Calcitriol (Active Vitamin D3)|'''Calcitriol''']]
*Increases phosphorus absorbtion from the intestines
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Calcitriol increases phosphorus absorption from the intestines.
  
 
==Pathology==
 
==Pathology==
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Diseases relating to phosphorus homeostasis include:
 
Diseases relating to phosphorus homeostasis include:
  
*[[Bones Metabolic - Pathology#Primary hyperparathyroidism |Primary and Secondary Hyperparathyroidism]]
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1. [[Hyperparathyroidism |Primary and Secondary Hyperparathyroidism]]
*[[Kidney Renal Failure - Pathology#Uraemia |Hyperphosphataemia]]
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*Hypophosphatemia
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2. Hyperphosphataemia
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3. Hypophosphatemia
  
==Test yourself with the Phosphorus Homeostasis Flashcards==
 
  
[[Phosphorus_Homeostasis_Flash_Cards_- Anatomy & Physiology|Phosphorus Homeostasis Flashcards]]
 
  
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{{Template:Learning
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|flashcards = [[Phosphorus_Homeostasis_Flash_Cards_- Anatomy & Physiology|Phosphorus homeostasis]].
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}}
  
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{{OpenPages}}
 
[[Category:Endocrine System - Anatomy & Physiology]]
 
[[Category:Endocrine System - Anatomy & Physiology]]
 
[[Category:Electrolytes]]
 
[[Category:Electrolytes]]
[[Category:To Do - A&P]]
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[[Category:A&P Done]]
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[[Category:Minerals]]

Latest revision as of 16:22, 12 April 2022


Overview

Phosphorus is the third most abundant intracellular ion:

1. Potassium

2. Magnesium

3. Phosphorus (as Phosphate)

Within the body it is found as Phosphate ions, or Phosphate within bone. The majority (~95%) is combined with Calcium in bone, forming Hydroxyapatite. Less than 1% is found in the extracelullar fluid.

Homeostasis

Serum concentrations of phosphorus are maintained by dietary sources. It is absorbed across the intestine via passive diffusion and vitamin D mediated active transport. Phosphorus is excreted in the urine or saliva (particularly in ruminants).

Hormonal Regulation

PTH

PTH mobilises phosphorus from bone, acting to increase the plasma concentration of P. It increases phosphorus loss in the urine and saliva, so ultimately, PTH acts to remove phosphorus from the body entirely.

Calcitriol

Calcitriol increases phosphorus absorption from the intestines.

Pathology

Diseases relating to phosphorus homeostasis include:

1. Primary and Secondary Hyperparathyroidism

2. Hyperphosphataemia

3. Hypophosphatemia



Phosphorus Learning Resources
FlashcardsFlashcards logo.png
Flashcards
Test your knowledge using flashcard type questions
Phosphorus homeostasis.



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