Difference between revisions of "Muscles Degenerative - Pathology"

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==Degeneration==
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#redirect[[:Category:Muscles - Degenerative Pathology]]
[[Image:Degenerate muscle fibres.jpg|right|thumb|100px|<small><center>Degenerate muscle fibres (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
 
 
 
*Different types of degeneration
 
*May, or may not, be reversible
 
*Cloudy swelling, hydropic, vacuolar, granular and fatty change
 
*Occur following many different types of insult and are usually '''segmental'''
 
*If regeneration does not occur after formation of small vacuoles, [[Muscles Degenerative - Pathology#Necrosis|necrosis]] follows
 
**Vacuolation -> floccular degeneration -> granular degeneration -> [[Hyaline Degeneration|hyaline]] and [[Zenker Degeneration - Pathology|Zenker’s degeneration]]
 
*[[Hydropic Degeneration#Vacuolar Degeneration|'''Vacuolar degeneration''']]:  
 
**Due to swelling of organelles or due to glycogen or fat accumulation
 
**May be caused by hypokalaemia, hyperkalaemia or necrosis
 
*Histologically:
 
**Swollen
 
**Hypereosinophilic
 
**Lost cross striations
 
 
 
 
 
===[[Muscle Calcification]]===
 
 
 
 
 
 
 
 
 
 
 
===[[Muscle Ossification]]===
 
 
 
 
 
===[[Muscle Pigmentation]]===
 
 
 
 
 
 
 
==[[Muscle Necrosis]]==
 
 
 
 
 
 
 
==[[Muscle Atrophy]]==
 
 
 
 
 
==[[Toxic Myopathy]]==
 
 
 
 
 
 
 
==[[Endocrine Myopathy]]==
 
 
 
 
 
 
 
 
 
==Nutritional myopathy==
 
 
 
===[[White Muscle Disease|White muscle disease]]===
 
 
 
 
 
==Exertional myopathies==
 
 
 
*Caused by intensive and exhaustive activity of major muscle masses
 
*Glycogen used up -> local heat and lactic acid -> muscle degeneration
 
*Other forms include '''capture myopathy''', racing greyhounds, sheep chased by dogs
 
 
 
 
 
===[[Equine Rhabdomyolysis]]===
 
 
 
 
 
 
 
 
 
===[[Porcine Stress Syndrome]]===
 
 
 
==Neuromuscular junction diseases==
 
 
 
===Aquired myasthenia gravis===
 
 
 
*See [[Myasthenia Gravis|congenital MG]]
 
 
 
 
 
===[[Botulism]]===
 
 
 
==Circulatory disturbances==
 
 
 
===[[Muscle Congestion]]===
 
 
 
 
 
===[[Muscle Ischaemia]]===
 
 
 
 
 
==[[Muscle Trauma]]==
 
 
 
 
 
 
 
[[Category:Musculoskeletal System - Pathology]]
 

Latest revision as of 18:20, 3 March 2011