Difference between revisions of "Rabbit Medicine and Surgery Q&A 19"
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Antibiotic-associated diarrhoea and enterotoxaemia. <br><br> | Antibiotic-associated diarrhoea and enterotoxaemia. <br><br> | ||
− | In rabbits, antibiotics, especially ampicillin, amoxycillin and amoxycillin-clavulanate, can alter the intestinal flora, leading to bacterial overgrowth of pathogenic species such as Clostridia spp. | + | In rabbits, antibiotics, especially ampicillin, amoxycillin and amoxycillin-clavulanate, can alter the intestinal flora, leading to bacterial overgrowth of pathogenic species such as ''Clostridia'' spp. |
<br><br> | <br><br> | ||
Amoxycillin-clavulanate is a high-risk antibiotic when given via any route and is contraindicated in rabbits. | Amoxycillin-clavulanate is a high-risk antibiotic when given via any route and is contraindicated in rabbits. | ||
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|q2=What is the prognosis? | |q2=What is the prognosis? | ||
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− | The prognosis in this case is extremely poor. Clostridia spp. multiply, resulting in enterotoxaemia, dehydration, electrolyte loss and acute death. Aggressive treatment is necessary if this rabbit is to survive. | + | The prognosis in this case is extremely poor. ''Clostridia'' spp. multiply, resulting in enterotoxaemia, dehydration, electrolyte loss and acute death. Aggressive treatment is necessary if this rabbit is to survive. |
|l2=Antibiotic-Associated Dysbacteriosis#Treatment | |l2=Antibiotic-Associated Dysbacteriosis#Treatment | ||
|q3=What are the treatment options? | |q3=What are the treatment options? | ||
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*Cholestyramine is an ion exchange resin that absorbs enterotoxins and may be useful if given early on. | *Cholestyramine is an ion exchange resin that absorbs enterotoxins and may be useful if given early on. | ||
*Probiotics are of questionable use; however, they are unlikely to cause any harm and may be of some benefit. | *Probiotics are of questionable use; however, they are unlikely to cause any harm and may be of some benefit. | ||
− | *Metronidazole may be administered to act against anaerobic Clostridia spp. | + | *Metronidazole may be administered to act against anaerobic ''Clostridia'' spp. |
*Analgesics may be indicated. | *Analgesics may be indicated. | ||
*If GI stasis has occurred, motility modifiers such as metoclopramide should be administered. | *If GI stasis has occurred, motility modifiers such as metoclopramide should be administered. |
Latest revision as of 18:01, 24 September 2011
This question was provided by Manson Publishing as part of the OVAL Project. See more Rabbit Medicine and Surgery questions |
A colleague has been treating an eight-month-old rabbit with a respiratory tract infection with a long-acting s/c injection of amoxycillin-clavulanate. Two days later the rabbit has developed acute diarrhoea and is presented in a collapsed state.
Question | Answer | Article | |
What is the most likely diagnosis? | Antibiotic-associated diarrhoea and enterotoxaemia. |
Link to Article | |
What is the prognosis? | The prognosis in this case is extremely poor. Clostridia spp. multiply, resulting in enterotoxaemia, dehydration, electrolyte loss and acute death. Aggressive treatment is necessary if this rabbit is to survive. |
Link to Article | |
What are the treatment options? | Treatment is often unsuccessful.
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Link to Article |