Difference between revisions of "Shigella"
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*Not significant cause of infection in domestic animals | *Not significant cause of infection in domestic animals | ||
| − | *Causes | + | *Causes dysentery in humans and primates |
*Enteroinvasive, invading the intestinal mucosa and causing necrosis | *Enteroinvasive, invading the intestinal mucosa and causing necrosis | ||
*Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream | *Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream | ||
*A large plasmid permits survival in cells and is responsible for invasivenss | *A large plasmid permits survival in cells and is responsible for invasivenss | ||
| − | *Closely related to ''E. coli'' - some strains produce Shiga toxin which is related to vero cytotoxin of ''E. coli'' | + | *Closely related to [[Escherichia coli|''E. coli'']] - some strains produce Shiga toxin which is related to vero cytotoxin of ''E. coli'' |
| + | |||
| + | * Cause of dysentery in humans and primates. | ||
| + | |||
| + | ===Dysentery in Humans and Primates=== | ||
| + | |||
| + | * [[Shigella|''Shigella'']] is are enteroinvasive, | ||
| + | ** Penetrate the intestinal mucosa. | ||
| + | ** Cause necrosis in patches of mucosa. | ||
| + | * [[Shigella|''Shigella'']] do not invade beyond the lamina propria to the bloodstream. | ||
| + | * Invasive potential is carried by a large plasmid. | ||
| + | ** Relates to the ability to survive inside the host cells. | ||
| + | * Some strains produce Shiga toxin. | ||
| + | ** Related to vero cytotoxin of some pathogenic strains of [[Escherichia coli|''E.coli'']]. | ||
| + | |||
| + | [[Category:Enterobacteriaceae]] | ||
| + | [[Category:Enteritis,_Bacterial]] | ||
| + | [[Category:To_Do_-_Bacteria]] | ||
Latest revision as of 10:44, 25 June 2010
- Not significant cause of infection in domestic animals
- Causes dysentery in humans and primates
- Enteroinvasive, invading the intestinal mucosa and causing necrosis
- Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream
- A large plasmid permits survival in cells and is responsible for invasivenss
- Closely related to E. coli - some strains produce Shiga toxin which is related to vero cytotoxin of E. coli
- Cause of dysentery in humans and primates.
Dysentery in Humans and Primates
- Shigella is are enteroinvasive,
- Penetrate the intestinal mucosa.
- Cause necrosis in patches of mucosa.
- Shigella do not invade beyond the lamina propria to the bloodstream.
- Invasive potential is carried by a large plasmid.
- Relates to the ability to survive inside the host cells.
- Some strains produce Shiga toxin.
- Related to vero cytotoxin of some pathogenic strains of E.coli.