Difference between revisions of "Morantel"

Latest revision as of 21:35, 29 September 2009

It belongs to the tetrahydropyrimidines class of drugs, which are known by farmers as yellow drenches. The product code in the UK is 2-LM.

This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
It has limited activity against larval forms and so has little uses.
Morantel is used in some rumenal boluses.
Pyrantel, a similar product, is used against equine cestodes.

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-These belong to the tetrahydropyrimidines class of drugs and a known by farmers as yellow drenches. The product code in the UK is '''2-LM'''.
+It belongs to the tetrahydropyrimidines class of drugs, which are known by farmers as yellow drenches. The product code in the UK is '''2-LM'''.
-==Levamisole==
-* This is one of the most widely used anthelmintics and can be given orally, by injection or as a pour on.
-* It is active against adult '''[[Nematodes]]''', but has limited action against the larval stages, especially the hypobiotic phase.
-* It is a cholinergic agonist at neural and nuromuscular junctions causing a '''spastic paralysis''' of the nematode. The nematodes succumb rapidly to it.
-* It is rapidly absorbed and excreted and it's potency is related to it's peak plasma concentration. Therefore pour-on products need a higher dose, as they are absorbed more slowly, to reach the same plasma concentrations.
-==Morantel==
 * This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
 * It has limited activity against larval forms and so has little uses.
 * Morantel is used in some rumenal boluses.
-* Pyrantel, a similar product, is used for against equine [[cestodes]].
+* Pyrantel, a similar product, is used against equine [[cestodes]].