Difference between revisions of "Category:Corynebacterium species"

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|pagebody =<div style="text-align: left; direction: ltr; margin-left: 1em;">The ''Corynebacterium'' are small, tough, Gram positive rods. They are common inhabitants of the skin and mucous membranes of animals and cause pyogenic, opportunistic infections.</div>
 
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<categorytree mode=pages>Corynebacterium species</categorytree>
 
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===Overview===
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[[Category:Bacterial Organisms]]
 
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[[Category:Gram_positive_bacteria]]
*Common inhabitants of skin and mucous membranes of animals
 
*Opportunistic infections
 
*Cause pyogenic infections
 
*Most species host specific
 
 
 
===Characteristics===
 
 
 
*Small, tough, Gram positive rods
 
*Pleomorphic
 
*Cluster together to resemble Chinese characters - coryneform morphology
 
*Known as diphtheroids
 
*Catalase positive, oxidase negative
 
*Facultative anaerobes
 
*Require enriched media for growth
 
*Non-motile
 
 
 
===Pathogenesis and pathogenicity===
 
 
 
*Pyogenic causing suppurative infections except for ''C. bovis''
 
*''C. pseudotuberculosis'':
 
**Facultative intracellular pathogen inside macrophages
 
**Cell wall lipid
 
**Produces a phospholipase toxin which hydolyses sphingomyelin in mammalian cell membranes
 
**Phospholipase may enhance survival and multiplication in host in early stages
 
*''C. renale''
 
**Urinary tract pathogens
 
**Produce urease and hydrolyse urea
 
**Possess fimbriae for attachment to urogenital mucosa
 
**Infection when immunity reduced or following tissue damage during parturition
 
 
 
===Diagnosis===
 
 
 
*Samples include pus, exudate, affected tissues and urine
 
*Presence of coryneform organisms in smears
 
*Culture on blood agar, selective blood agar and MacConkey agar
 
*Do not grow on MacConkey
 
*Colony characteristics:
 
**''C. bovis'': lipophilic bacterium; small, white, dry, non-haemolytic colonies on plates inoculated with bovine milk
 
**''C. kutscheri'': white colonies; occasionally haemolytic
 
**''C. pseudotuberculosis'': small, white coloniess surrounded by narrow zone of complete haemolysis; colonies become dry and cream-coloured
 
**''C. renale'': small, non-haemolytic colonies after 24 hours; pigment produced after 48 hours
 
*Biochemical reactions:
 
**Certain strains of ''C. pseudotuberculosis'' reduce nitrates
 
**All pathogenic strains except ''C. bovis'' produce urease
 
*Enhancement of haemolysis produced by ''C. pseudotuberculosis'' when inoculated across a streak of ''Rhodococcus equi''
 
 
 
[[Category:Bacteria]][[Category:Gram_positive_bacteria]]
 
 
[[Category:Rods]]
 
[[Category:Rods]]

Latest revision as of 21:26, 5 November 2010

Corynebacterium species

The Corynebacterium are small, tough, Gram positive rods. They are common inhabitants of the skin and mucous membranes of animals and cause pyogenic, opportunistic infections.

Pages in category "Corynebacterium species"

The following 5 pages are in this category, out of 5 total.