Difference between revisions of "Shigella"
Jump to navigation
Jump to search
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
*Not significant cause of infection in domestic animals | *Not significant cause of infection in domestic animals | ||
| − | *Causes | + | *Causes dysentery in humans and primates |
*Enteroinvasive, invading the intestinal mucosa and causing necrosis | *Enteroinvasive, invading the intestinal mucosa and causing necrosis | ||
*Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream | *Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream | ||
| Line 21: | Line 21: | ||
[[Category:Enterobacteriaceae]] | [[Category:Enterobacteriaceae]] | ||
[[Category:Enteritis,_Bacterial]] | [[Category:Enteritis,_Bacterial]] | ||
| + | [[Category:To_Do_-_Bacteria]] | ||
Latest revision as of 10:44, 25 June 2010
- Not significant cause of infection in domestic animals
- Causes dysentery in humans and primates
- Enteroinvasive, invading the intestinal mucosa and causing necrosis
- Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream
- A large plasmid permits survival in cells and is responsible for invasivenss
- Closely related to E. coli - some strains produce Shiga toxin which is related to vero cytotoxin of E. coli
- Cause of dysentery in humans and primates.
Dysentery in Humans and Primates
- Shigella is are enteroinvasive,
- Penetrate the intestinal mucosa.
- Cause necrosis in patches of mucosa.
- Shigella do not invade beyond the lamina propria to the bloodstream.
- Invasive potential is carried by a large plasmid.
- Relates to the ability to survive inside the host cells.
- Some strains produce Shiga toxin.
- Related to vero cytotoxin of some pathogenic strains of E.coli.