Difference between revisions of "Nasal Cavity Hyperplastic and Neoplastic - Pathology"

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#REDIRECT[[:Category:Nasal Cavity - Hyperplastic/Neoplastic Pathology]]
 
 
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|linkpage =Cardiorespiratory System - Pathology
 
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|sublink1=Nasal Cavity - Pathology
 
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[[Image:Fibrosarcoma in rhinarium of cat.jpg|right|thumb|100px|<small><center>Fibrosarcoma in rhinarium of a cat (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
 
[[Image:Lymphoma in nasal cavity.jpg|right|thumb|100px|<small><center>Lymphoma in nasal cavity (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
 
[[Image:Nasal cavity carcinoma.jpg|right|thumb|100px|<small><center>Nasal cavity carcinoma (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
 
 
 
 
 
 
 
===Nasal neoplasia in general===
 
 
 
*Majority are malignant, locally invasive but do not metastasise
 
*Usually pale, soft, fleshy or friable
 
*May be [[Bones Hyperplastic and Neoplastic - Pathology|osteoma or osteosarcoma, chondroma or chondrosarcoma]], fibroma or fibrosarcoma, myxoma or myxosarcoma, haemangioma or haemangiosarcoma, adenoma or adenocarcinoma
 
 
 
 
 
===Adenocarcinoma===
 
 
 
*Most common in dogs, also sheep
 
*Glandular acini in layer of cuboidal or columnar epithelium
 
*Often mucin filled acini
 
 
 
 
 
===Transitional cell carcinoma===
 
 
 
*Most common in dogs
 
*Thick stratified layer of cuboidal cells with distinct basement membrane
 
*Large growth may be separated by fibrovascular septa
 
*May contain microcysts that could be confused with adenocarcinoma above
 
 
 
 
 
===Squamous cell carcinoma===
 
 
 
*In cats they arise mainly from nasal vestibule
 
*In horses they originate mainly from maxillary sinus
 
*Most common nasal tumour
 
**Serosanquineous or mucopurulent, odourous nasal discharge
 
*Tissue necrosis
 
*May cause airway obstruction or facial distortion
 
 
 
 
 
===Olfactory neuroblastoma===
 
 
 
*Rare, mainly occurs in cats
 
*Arises from ethmoturbinates in caudal region of nasal cavity
 
*May penetrate cribriform plate into cerebral cortex
 
 
 
 
 
===Ethmoturbinate tumours (papillomas and adenocarcinomas)===
 
 
 
*In horses and other species
 
*Multiple species may be affected on one premises
 
*Arising from olfactory cells are endemic in some parts of the world for unknown reason
 
*May be caused by a virus?
 
 
 
 
 
===Progressive ethmoidal haematoma===
 
 
 
*Slowly expanding non-neoplastic mass of horses
 
*Originates from submucosa of ethmoidal labyrinth
 
*Either from nasal or sinusal portion of ethmoid labyrinth
 
*Unilateral, can extend to nostrils or choanae
 
*Rarely elsewhere in sinuses
 
*Expands to nasal cavity, [[Paranasal Sinuses Hyperplastic and Neoplastic - Pathology|paranasal sinuses]], [[Nasopharynx Hyperplastic and Neoplastic - Pathology|nasopharynx]] causing destruction of tissue
 
*Micro - haemorrhage, calcification of connective tissue fibres
 
*[[Aspergillus spp.|''Aspergillus'' spp.]] may be present on the lesion
 
*May cause [[Respiratory System Clinical Signs - Pathology#Epistaxis|epistaxis]]
 
*Can recur after surgical excision
 
*May arise subsequently to [[Nasal Cavity Inflammatory - Pathology#Chronic rhinitis|chronic inflammation]]
 
 
 
 
 
===Nasal polyps===
 
 
 
*Polypoid thickening of the inflamed nasal musosa, hyperplastic epithelium
 
*Pinkish, often pedunculated masses, round, often large and multiple proturberences into the nasal meatus
 
*Can arise subsequently to [[Nasal Cavity Inflammatory - Pathology#Chronic rhinitis|chronic inflammation]]
 
*Old polyps may becoma fibrous
 
*May recur when excised
 
*Necessary to distinguish from neoplasia
 
*Common in cats, less often in dogs, also horses and sheep
 
*Also see [[Nasal Cavity Hyperplastic and Neoplastic - Pathology#Progressive ethmoidal haematoma|Progressive haematoma]] of horses and [[Nasopharynx Hyperplastic and Neoplastic - Pathology#Nasopharyngeal polyps of cats|Nasopharyngeal polyps]] of cats
 
 
 
 
 
===Nasal and paranasal sinus cysts===
 
 
 
*Mimic infection or neoplasms
 
*Expand and destroy surrounding tissue
 
*Epithelial capsule with haemorrhagic or yellow fluid
 
*Do not tend to recur after surgery
 
 
 
==Test yourself with the Nasal Cavity Pathology Flashcards==
 
 
 
[[Nasal_Cavity_Flashcards_-_Pathology|Nasal Cavity Pathology Flashcards]]
 

Latest revision as of 18:08, 15 February 2011