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Omega-6 Fatty Acids - Nutrition (view source)
Revision as of 08:41, 15 May 2015
, 08:41, 15 May 2015no edit summary
==Roles in the Body==
==Roles in the Body==
#'''Skin and Hair Coat:''' Epidermal keratinocytes secrete the LA-enriched phospholipid, ceramide, in both dogs and cats. Ceramide functions to enhance cell cohesion and create an effective water barrier<ref name="Elias"/>. Increased intake of LA above the minimal requirement may improve skin and coat health in dogs and cats<ref name="Rees"/><ref name="Codner"/>.
#'''Skin and Hair Coat:''' Epidermal keratinocytes secrete the LA-enriched phospholipid, ceramide, in both dogs and cats. Ceramide functions to enhance cell cohesion and create an effective water barrier<ref name="Elias"/>. Increased intake of LA above the minimal requirement may improve skin and coat health in dogs and cats<ref name="Rees"/><ref name="Codner"/>.
#'''Inflammation:''' Arachidonic acid comprises approximately 20-25% of the fatty acids within the cellular membrane and acts as a substrate for cyclooxygenase (COX) and lipoxygenase (LOX) enzymes to form the inflammatory eicosanoids series-2 prostaglandins (prostaglandins, prostycyclins and thromboxanes) and series-4 leukotrienes<ref name="NRC"/>.
#'''Inflammation:''' Arachidonic acid comprises approximately 20-25% of the fatty acids within the cellular membrane and acts as a substrate for cyclooxygenase (COX) and lipoxygenase (LOX) enzymes to form the inflammatory [[Nutrition Glossary#Eicosanoids|eicosanoids]] series-2 prostaglandins (prostaglandins, prostycyclins and thromboxanes) and series-4 leukotrienes<ref name="NRC"/>.
#'''Reproduction:''' Queens fed AA deficient diets with adequate levels of LA are unable to support normal pregnancy and foetal development<ref name="MacDonald">MacDonald ML, et al. Effects of linoleate and arachidonate deficiency on reproduction and spermatogenesis in the cat. J Nutr 1984;114:719-726.</ref>, while no impact on male fertility and spermatogenesis is seen.
#'''Reproduction:''' Queens fed AA deficient diets with adequate levels of LA are unable to support normal pregnancy and foetal development<ref name="MacDonald">MacDonald ML, et al. Effects of linoleate and arachidonate deficiency on reproduction and spermatogenesis in the cat. J Nutr 1984;114:719-726.</ref>, while no impact on male fertility and spermatogenesis is seen.
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