Changes

====Vacuolar Degeneration====

====Vacuolar Degeneration====

the second type, the excess water is transferred to the

* In vacuolar degeneration, excess water is transferred to the endoplasmic reticulum (ER).

endoplasmic reticulum (ER) which swells and eventually fragments, leaving a fluid vacuole

* The ER  swells and eventually fragments.

in the cytoplasm. It commonly occurs in cells such as the hepatocyte, renal tubular

** A fluid vacuole remains in the cytoplasm.  

epithelium and pancreatic acinar cell which are very metabolically active and have welldeveloped

* Commonly occurs in cells that are very metabolically active and have well developed pumping mechanisms.

pumping mechanisms.

** E.g. as the hepatocyte, renal tubular epithelium and pancreatic acinar cell.

===Cellular Fatty Change===

===Cellular Fatty Change===