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The clinical features of cyathostomosis are relatively non-specific and confirming a diagnosis of cyathostomosis may be difficult. Faecal egg counts may not be useful as large numbers of eggs in the faeces do not always indcate a pathological worm burden. Affected horses may show the following abnormalities on haematology and biochemistry:
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The clinical features of cyathostomosis are relatively non-specific and confirming a diagnosis may be difficult. Faecal egg counts may not be useful as large numbers of eggs in the faeces do not always indcate a pathological worm burden. Affected horses may show the following abnormalities on haematology and biochemistry:
    
* Hyperglobulinaemia (especially IgG)
 
* Hyperglobulinaemia (especially IgG)
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* Neutrophilia
 
* Neutrophilia
 
* Hypoalbuminaemia
 
* Hypoalbuminaemia
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* Increased ALP
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* Hypoproteinaemia
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Gross examination of faeces may reveal large numbers of small, thread like larvae. Larvae may also be found on the plastic sleeve following rectal examination.   
 
Gross examination of faeces may reveal large numbers of small, thread like larvae. Larvae may also be found on the plastic sleeve following rectal examination.   
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Intestinal biopsy via laparotomy may may reveal a massive eosinophilic infiltration of the mucosa.  
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A definitive diagnosis of cyathostomosis may be made following identification of larvae in the gastrointestinal tract, either in the faeces, from an intestinal biopsy via laparotomy, or at post mortem. Biopsy may also reveal a massive eosinophilic infiltration of the mucosa.  
     
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